Halogen-magnesium exchange on unprotected aromatic and heteroaromatic carboxylic acids

Felix Kopp, Stefan Wunderlich, Paul Knochel

Research output: Contribution to journalArticlepeer-review

38 Scopus citations

Abstract

The magnesiation of halogenated aromatic and heteroaromatic carboxylic acids is accomplished by their treatment with MeMgCl in the presence of LiCl and subsequent reaction with i-PrMgCl·LiCl; the resulting double-magnesiated species react with a variety of electrophiles in up to 97% yield.

Original languageEnglish (US)
Pages (from-to)2075-2077
Number of pages3
JournalChemical Communications
Issue number20
DOIs
StatePublished - Jan 1 2007

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Fingerprint Dive into the research topics of 'Halogen-magnesium exchange on unprotected aromatic and heteroaromatic carboxylic acids'. Together they form a unique fingerprint.

Cite this