Guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder and posttraumatic stress disorder in primary care

Borwin Bandelow, Leo Sher, Robertas Bunevicius, Eric Hollander, Siegfried Kasper, Joseph Zohar, Hans Jürgen Möller, Florence Thibaut, Wioletta Baranska-Rybak, Wieclaw J. Cubala, David Fiellin, Henry R. Kranzler, Alison Moore, Elmars Rankans, Jill Rasmussen, Richard Saitz, Djea Saravane, Thomas E. Schlaepfer, S. W. Tang, Leonas ValiusDavid Wong, Larisa M. Zhitnikova, C. Allgulander, J. Ayuso-Gutierrez, D. Baldwin, R. Bunevicius, G. Cassano, N. Fineberg, L. Gabriels, I. Hindmarch, H. Kaiya, D. F. Klein, M. Lader, Y. Lecrubier, J. P. Lepine, M. R. Liebowitz, J. J. Lopez-Ibor, D. Marazitti, E. C. Miguel, K. S. Oh, M. Preter, R. Rupprecht, M. Sato, V. Starcevic, D. J. Stein, M. Van Ameringen, J. Vega

Research output: Contribution to journalReview article

228 Scopus citations

Abstract

Objective. Anxiety disorders are frequently under-diagnosed conditions in primary care, although they can be managed effectively by general practitioners. Methods. This paper is a short and practical summary of the World Federation of Biological Psychiatry (WFSBP) guidelines for the pharmacological treatment of anxiety disorders, obsessivecompulsive disorder (OCD) and posttraumatic stress disorder (PTSD) for the treatment in primary care. The recommendations were developed by a task force of 30 international experts in the field and are based on randomized controlled studies. Results. First-line pharmacological treatments for these disorders are selective serotonin reuptake inhibitors (for all disorders), serotonin-norepinephrine reuptake inhibitors (for some) and pregabalin (for generalized anxiety disorder only). A combination of medication and cognitive behavior/exposure therapy was shown to be a clinically desired treatment strategy. Conclusions. This short version of an evidence-based guideline may improve treatment of anxiety disorders, OCD, and PTSD in primary care.

Original languageEnglish (US)
Pages (from-to)77-84
Number of pages8
JournalInternational Journal of Psychiatry in Clinical Practice
Volume16
Issue number2
DOIs
StatePublished - Jun 2012

Keywords

  • Anxiety disorders
  • Generalized anxiety disorder
  • Guidelines
  • Panic disorder
  • Pharmacological treatment
  • Social anxiety disorder

ASJC Scopus subject areas

  • Psychiatry and Mental health

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    Bandelow, B., Sher, L., Bunevicius, R., Hollander, E., Kasper, S., Zohar, J., Möller, H. J., Thibaut, F., Baranska-Rybak, W., Cubala, W. J., Fiellin, D., Kranzler, H. R., Moore, A., Rankans, E., Rasmussen, J., Saitz, R., Saravane, D., Schlaepfer, T. E., Tang, S. W., ... Vega, J. (2012). Guidelines for the pharmacological treatment of anxiety disorders, obsessive-compulsive disorder and posttraumatic stress disorder in primary care. International Journal of Psychiatry in Clinical Practice, 16(2), 77-84. https://doi.org/10.3109/13651501.2012.667114