Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52-Variant Lineages

Chuqing Zhang, Jong Sup Park, Grce Magdalena, Samantha Hibbitts, Joel M. Palefsky, Ryo Konno, Karen K. Smith-McCune, Lucia Giovannelli, Tang Yuan Chu, María Alejandra Picconi, Patricia Piña-Sánchez, Wannapa Settheetham-Ishida, Francois Coutlée, Federico De Marco, Yin Ling Woo, Wendy C S Ho, Martin C S Wong, Mike Z. Chirenje, Tsitsi Magure, Anna Barbara Moscicki & 7 others Ivan Sabol, Alison N. Fiander, Zigui Chen, Martin C W Chan, Tak Hong Cheung, Robert D. Burk, Paul K S Chan

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Human papillomavirus (HPV) genotype 52 is commonly found in Asian cases of cervical cancer but is rare elsewhere. Analysis of 611 isolates collected worldwide revealed a remarkable geographical distribution, with lineage B predominating in Asia (89.0% vs 0%-5.5%; P<inf>corrected</inf> <. 001), whereas lineage A predominated in Africa, the Americas, and Europe. We propose that the name "Asian lineage" be used to denote lineage B, to signify this feature. Preliminary analysis suggested a higher disease risk for lineage B, although ethnogeographical confounders could not be excluded. Further studies are warranted to verify whether the reported high attribution of disease to HPV52 in Asia is due to the high prevalence of lineage B.

Original languageEnglish (US)
Pages (from-to)1600-1604
Number of pages5
JournalJournal of Infectious Diseases
Volume210
Issue number10
DOIs
StatePublished - Nov 15 2014

Fingerprint

Genotype
Uterine Cervical Neoplasms
Names

Keywords

  • Asia.
  • cervical cancer
  • HPV
  • oncogenic risk
  • phylogeny

ASJC Scopus subject areas

  • Infectious Diseases
  • Immunology and Allergy
  • Medicine(all)

Cite this

Zhang, C., Park, J. S., Magdalena, G., Hibbitts, S., Palefsky, J. M., Konno, R., ... Chan, P. K. S. (2014). Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52-Variant Lineages. Journal of Infectious Diseases, 210(10), 1600-1604. https://doi.org/10.1093/infdis/jiu310

Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52-Variant Lineages. / Zhang, Chuqing; Park, Jong Sup; Magdalena, Grce; Hibbitts, Samantha; Palefsky, Joel M.; Konno, Ryo; Smith-McCune, Karen K.; Giovannelli, Lucia; Chu, Tang Yuan; Picconi, María Alejandra; Piña-Sánchez, Patricia; Settheetham-Ishida, Wannapa; Coutlée, Francois; De Marco, Federico; Woo, Yin Ling; Ho, Wendy C S; Wong, Martin C S; Chirenje, Mike Z.; Magure, Tsitsi; Moscicki, Anna Barbara; Sabol, Ivan; Fiander, Alison N.; Chen, Zigui; Chan, Martin C W; Cheung, Tak Hong; Burk, Robert D.; Chan, Paul K S.

In: Journal of Infectious Diseases, Vol. 210, No. 10, 15.11.2014, p. 1600-1604.

Research output: Contribution to journalArticle

Zhang, C, Park, JS, Magdalena, G, Hibbitts, S, Palefsky, JM, Konno, R, Smith-McCune, KK, Giovannelli, L, Chu, TY, Picconi, MA, Piña-Sánchez, P, Settheetham-Ishida, W, Coutlée, F, De Marco, F, Woo, YL, Ho, WCS, Wong, MCS, Chirenje, MZ, Magure, T, Moscicki, AB, Sabol, I, Fiander, AN, Chen, Z, Chan, MCW, Cheung, TH, Burk, RD & Chan, PKS 2014, 'Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52-Variant Lineages', Journal of Infectious Diseases, vol. 210, no. 10, pp. 1600-1604. https://doi.org/10.1093/infdis/jiu310
Zhang, Chuqing ; Park, Jong Sup ; Magdalena, Grce ; Hibbitts, Samantha ; Palefsky, Joel M. ; Konno, Ryo ; Smith-McCune, Karen K. ; Giovannelli, Lucia ; Chu, Tang Yuan ; Picconi, María Alejandra ; Piña-Sánchez, Patricia ; Settheetham-Ishida, Wannapa ; Coutlée, Francois ; De Marco, Federico ; Woo, Yin Ling ; Ho, Wendy C S ; Wong, Martin C S ; Chirenje, Mike Z. ; Magure, Tsitsi ; Moscicki, Anna Barbara ; Sabol, Ivan ; Fiander, Alison N. ; Chen, Zigui ; Chan, Martin C W ; Cheung, Tak Hong ; Burk, Robert D. ; Chan, Paul K S. / Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52-Variant Lineages. In: Journal of Infectious Diseases. 2014 ; Vol. 210, No. 10. pp. 1600-1604.
@article{ece749e003e04b7eb951b3e198deee79,
title = "Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52-Variant Lineages",
abstract = "Human papillomavirus (HPV) genotype 52 is commonly found in Asian cases of cervical cancer but is rare elsewhere. Analysis of 611 isolates collected worldwide revealed a remarkable geographical distribution, with lineage B predominating in Asia (89.0{\%} vs 0{\%}-5.5{\%}; Pcorrected <. 001), whereas lineage A predominated in Africa, the Americas, and Europe. We propose that the name {"}Asian lineage{"} be used to denote lineage B, to signify this feature. Preliminary analysis suggested a higher disease risk for lineage B, although ethnogeographical confounders could not be excluded. Further studies are warranted to verify whether the reported high attribution of disease to HPV52 in Asia is due to the high prevalence of lineage B.",
keywords = "Asia., cervical cancer, HPV, oncogenic risk, phylogeny",
author = "Chuqing Zhang and Park, {Jong Sup} and Grce Magdalena and Samantha Hibbitts and Palefsky, {Joel M.} and Ryo Konno and Smith-McCune, {Karen K.} and Lucia Giovannelli and Chu, {Tang Yuan} and Picconi, {Mar{\'i}a Alejandra} and Patricia Pi{\~n}a-S{\'a}nchez and Wannapa Settheetham-Ishida and Francois Coutl{\'e}e and {De Marco}, Federico and Woo, {Yin Ling} and Ho, {Wendy C S} and Wong, {Martin C S} and Chirenje, {Mike Z.} and Tsitsi Magure and Moscicki, {Anna Barbara} and Ivan Sabol and Fiander, {Alison N.} and Zigui Chen and Chan, {Martin C W} and Cheung, {Tak Hong} and Burk, {Robert D.} and Chan, {Paul K S}",
year = "2014",
month = "11",
day = "15",
doi = "10.1093/infdis/jiu310",
language = "English (US)",
volume = "210",
pages = "1600--1604",
journal = "Journal of Infectious Diseases",
issn = "0022-1899",
publisher = "Oxford University Press",
number = "10",

}

TY - JOUR

T1 - Geographical Distribution and Risk Association of Human Papillomavirus Genotype 52-Variant Lineages

AU - Zhang, Chuqing

AU - Park, Jong Sup

AU - Magdalena, Grce

AU - Hibbitts, Samantha

AU - Palefsky, Joel M.

AU - Konno, Ryo

AU - Smith-McCune, Karen K.

AU - Giovannelli, Lucia

AU - Chu, Tang Yuan

AU - Picconi, María Alejandra

AU - Piña-Sánchez, Patricia

AU - Settheetham-Ishida, Wannapa

AU - Coutlée, Francois

AU - De Marco, Federico

AU - Woo, Yin Ling

AU - Ho, Wendy C S

AU - Wong, Martin C S

AU - Chirenje, Mike Z.

AU - Magure, Tsitsi

AU - Moscicki, Anna Barbara

AU - Sabol, Ivan

AU - Fiander, Alison N.

AU - Chen, Zigui

AU - Chan, Martin C W

AU - Cheung, Tak Hong

AU - Burk, Robert D.

AU - Chan, Paul K S

PY - 2014/11/15

Y1 - 2014/11/15

N2 - Human papillomavirus (HPV) genotype 52 is commonly found in Asian cases of cervical cancer but is rare elsewhere. Analysis of 611 isolates collected worldwide revealed a remarkable geographical distribution, with lineage B predominating in Asia (89.0% vs 0%-5.5%; Pcorrected <. 001), whereas lineage A predominated in Africa, the Americas, and Europe. We propose that the name "Asian lineage" be used to denote lineage B, to signify this feature. Preliminary analysis suggested a higher disease risk for lineage B, although ethnogeographical confounders could not be excluded. Further studies are warranted to verify whether the reported high attribution of disease to HPV52 in Asia is due to the high prevalence of lineage B.

AB - Human papillomavirus (HPV) genotype 52 is commonly found in Asian cases of cervical cancer but is rare elsewhere. Analysis of 611 isolates collected worldwide revealed a remarkable geographical distribution, with lineage B predominating in Asia (89.0% vs 0%-5.5%; Pcorrected <. 001), whereas lineage A predominated in Africa, the Americas, and Europe. We propose that the name "Asian lineage" be used to denote lineage B, to signify this feature. Preliminary analysis suggested a higher disease risk for lineage B, although ethnogeographical confounders could not be excluded. Further studies are warranted to verify whether the reported high attribution of disease to HPV52 in Asia is due to the high prevalence of lineage B.

KW - Asia.

KW - cervical cancer

KW - HPV

KW - oncogenic risk

KW - phylogeny

UR - http://www.scopus.com/inward/record.url?scp=84907191169&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84907191169&partnerID=8YFLogxK

U2 - 10.1093/infdis/jiu310

DO - 10.1093/infdis/jiu310

M3 - Article

VL - 210

SP - 1600

EP - 1604

JO - Journal of Infectious Diseases

JF - Journal of Infectious Diseases

SN - 0022-1899

IS - 10

ER -