Abstract
Gap junctions are clusters of intercellular channels directly connecting the cytoplasm of adjacent cells. These channels are formed by proteins named connexins and are present in all metazoan organisms where they serve diverse functions ranging from control of cell growth and differentiation to electric conduction in excitable tissues. In this overview we describe the presence of connexins in the cardiovascular and lympho-hematopoietic systems giving the reader a summary of the topics to be covered throughout this edition and a historical perspective of the discovery of gap junctions in the immune system.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 365-368 |
| Number of pages | 4 |
| Journal | Brazilian Journal of Medical and Biological Research |
| Volume | 33 |
| Issue number | 4 |
| DOIs | |
| State | Published - Apr 2000 |
| Externally published | Yes |
Keywords
- Cardiovascular system
- Connexins
- Gap junctions
- Immune system
ASJC Scopus subject areas
- General Pharmacology, Toxicology and Pharmaceutics
- Biophysics
- General Neuroscience
- Biochemistry
- Physiology
- Cell Biology
- Immunology