Gap junctions in the cardiovascular and immune systems

R. Rozental, A. C. Campos De Carvalho, D. C. Spray

Research output: Contribution to journalArticlepeer-review

12 Scopus citations


Gap junctions are clusters of intercellular channels directly connecting the cytoplasm of adjacent cells. These channels are formed by proteins named connexins and are present in all metazoan organisms where they serve diverse functions ranging from control of cell growth and differentiation to electric conduction in excitable tissues. In this overview we describe the presence of connexins in the cardiovascular and lympho-hematopoietic systems giving the reader a summary of the topics to be covered throughout this edition and a historical perspective of the discovery of gap junctions in the immune system.

Original languageEnglish (US)
Pages (from-to)365-368
Number of pages4
JournalBrazilian Journal of Medical and Biological Research
Issue number4
StatePublished - Apr 2000
Externally publishedYes


  • Cardiovascular system
  • Connexins
  • Gap junctions
  • Immune system

ASJC Scopus subject areas

  • Biophysics
  • Neuroscience(all)
  • Biochemistry
  • Physiology
  • Immunology
  • Pharmacology, Toxicology and Pharmaceutics(all)
  • Cell Biology


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