Gabapentin toxicity in children manifesting as behavioral changes

Research output: Contribution to journalArticle

106 Citations (Scopus)

Abstract

Pediatric experience with gabapentin (GBP), a new antiepileptic drug (AED), is limited. We describe 3 learning disabled children, 1 aged 7 years and 2 aged 10 years, with intractable partial seizures who developed severe behavioral problems while receiving modest doses of GBP. The children became hyperactive and had explosive outbursts consisting of aggressive and oppositional behavior. The behavioral problems were sufficiently severe to require discontinuation of GBP despite moderately improved seizure control.

Original languageEnglish (US)
Pages (from-to)1203-1205
Number of pages3
JournalEpilepsia
Volume36
Issue number12
DOIs
StatePublished - 1995

Fingerprint

Seizures
Disabled Children
Anticonvulsants
Learning
Pediatrics
gabapentin
Problem Behavior

Keywords

  • Anticonvulsants
  • Children's behavioral events
  • Gabapentin

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Gabapentin toxicity in children manifesting as behavioral changes. / Wolf, S. M.; Shinnar, Shlomo; Kang, H.; Ballaban-Gil, Karen R.; Moshe, Solomon L.

In: Epilepsia, Vol. 36, No. 12, 1995, p. 1203-1205.

Research output: Contribution to journalArticle

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