Further observations on peripheral neuropathy in the Syrian hamster with hind leg paralysis

Asao Hirano

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

Pathological alteration of peripheral nerves in the mutant Syrian hamster with hind-leg paralysis were examined under the electron microscope. The changes included alteration of axonal caliber and abnormal distribution of axoplasmic contents. In addition, changes at the inner loop: axonal interface were noted which included accumulation of filamentous and granular material in the axon, loss of the inner loop membrane, and discontinuity of the subjecent axonal membrane. Demyelination and onion bulb formation was seen in the older hamsters.

Original languageEnglish (US)
Pages (from-to)187-192
Number of pages6
JournalActa Neuropathologica
Volume50
Issue number3
DOIs
StatePublished - Jan 1980

Fingerprint

Paraplegia
Mesocricetus
Peripheral Nervous System Diseases
Onions
Membranes
Demyelinating Diseases
Peripheral Nerves
Cricetinae
Axons
Electrons

Keywords

  • Onion bulb formation
  • Peripheral neuropathy
  • Schwann cell: axonal interface

ASJC Scopus subject areas

  • Neuroscience(all)
  • Pathology and Forensic Medicine
  • Clinical Neurology

Cite this

Further observations on peripheral neuropathy in the Syrian hamster with hind leg paralysis. / Hirano, Asao.

In: Acta Neuropathologica, Vol. 50, No. 3, 01.1980, p. 187-192.

Research output: Contribution to journalArticle

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