Fine needle aspiration of urethral recurrence of urothelial carcinoma after radical cystectomy presenting as a perineal mass: A case report

Osama M. Al-Agha, Samer N. Khader, Antonio Cajigas, William Blank, Neil Grafstein, Andrew W. Seymour

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Background: Recurrence of urothelial (transitional cell) carcinoma in the urethra after cystectomy for invasive urothelial carcinoma is relatively uncommon. It is also uncommon for the recurring urethral tumor to present as a painful perineal mass. Fine needle aspiration (FNA) can be used to evaluate such perineal lesions and confirm tumor recurrence. Case: A 5-cm-diameter mass was found in the perineum of a 63-year-old man 1 year after radical cystoprostatectomy for invasive urothelial carcinoma of the urinary bladder. The mass was detected on pelvic computed tomographic scanning. FNA cytology showed numerous urothelial carcinoma cells of high grade displaying squamous cell differentiation mimicking the histopathologic findings of the primary tumor found on cystectomy. Diagnosis of recurrent urothelial carcinoma was rendered. The FNA in this case spared the patient an open biopsy. Conclusion: Mass lesions arising in the perineum of patients who underwent cystectomy for urothelial carcinoma should raise the suspicion of urothelial carcinoma recurrence. Evaluation of perineal masses for recurrence of urothelial carcinoma can be made on FNA without the need for open biopsy.

Original languageEnglish (US)
Pages (from-to)94-98
Number of pages5
JournalActa Cytologica
Volume52
Issue number1
StatePublished - 2008

Fingerprint

Cystectomy
Fine Needle Biopsy
Carcinoma
Recurrence
Perineum
Biopsy
Neoplasms
Transitional Cell Carcinoma
Urethra
Cell Biology
Cell Differentiation
Urinary Bladder
Epithelial Cells

Keywords

  • Aspiration cytology, fine-needle
  • Carcinoma, urothelial

ASJC Scopus subject areas

  • Anatomy
  • Cell Biology
  • Histology

Cite this

Fine needle aspiration of urethral recurrence of urothelial carcinoma after radical cystectomy presenting as a perineal mass : A case report. / Al-Agha, Osama M.; Khader, Samer N.; Cajigas, Antonio; Blank, William; Grafstein, Neil; Seymour, Andrew W.

In: Acta Cytologica, Vol. 52, No. 1, 2008, p. 94-98.

Research output: Contribution to journalArticle

@article{6c1cf49bfa38420990f87999328560bd,
title = "Fine needle aspiration of urethral recurrence of urothelial carcinoma after radical cystectomy presenting as a perineal mass: A case report",
abstract = "Background: Recurrence of urothelial (transitional cell) carcinoma in the urethra after cystectomy for invasive urothelial carcinoma is relatively uncommon. It is also uncommon for the recurring urethral tumor to present as a painful perineal mass. Fine needle aspiration (FNA) can be used to evaluate such perineal lesions and confirm tumor recurrence. Case: A 5-cm-diameter mass was found in the perineum of a 63-year-old man 1 year after radical cystoprostatectomy for invasive urothelial carcinoma of the urinary bladder. The mass was detected on pelvic computed tomographic scanning. FNA cytology showed numerous urothelial carcinoma cells of high grade displaying squamous cell differentiation mimicking the histopathologic findings of the primary tumor found on cystectomy. Diagnosis of recurrent urothelial carcinoma was rendered. The FNA in this case spared the patient an open biopsy. Conclusion: Mass lesions arising in the perineum of patients who underwent cystectomy for urothelial carcinoma should raise the suspicion of urothelial carcinoma recurrence. Evaluation of perineal masses for recurrence of urothelial carcinoma can be made on FNA without the need for open biopsy.",
keywords = "Aspiration cytology, fine-needle, Carcinoma, urothelial",
author = "Al-Agha, {Osama M.} and Khader, {Samer N.} and Antonio Cajigas and William Blank and Neil Grafstein and Seymour, {Andrew W.}",
year = "2008",
language = "English (US)",
volume = "52",
pages = "94--98",
journal = "Acta Cytologica",
issn = "0001-5547",
publisher = "Science Printers and Publishers Inc.",
number = "1",

}

TY - JOUR

T1 - Fine needle aspiration of urethral recurrence of urothelial carcinoma after radical cystectomy presenting as a perineal mass

T2 - A case report

AU - Al-Agha, Osama M.

AU - Khader, Samer N.

AU - Cajigas, Antonio

AU - Blank, William

AU - Grafstein, Neil

AU - Seymour, Andrew W.

PY - 2008

Y1 - 2008

N2 - Background: Recurrence of urothelial (transitional cell) carcinoma in the urethra after cystectomy for invasive urothelial carcinoma is relatively uncommon. It is also uncommon for the recurring urethral tumor to present as a painful perineal mass. Fine needle aspiration (FNA) can be used to evaluate such perineal lesions and confirm tumor recurrence. Case: A 5-cm-diameter mass was found in the perineum of a 63-year-old man 1 year after radical cystoprostatectomy for invasive urothelial carcinoma of the urinary bladder. The mass was detected on pelvic computed tomographic scanning. FNA cytology showed numerous urothelial carcinoma cells of high grade displaying squamous cell differentiation mimicking the histopathologic findings of the primary tumor found on cystectomy. Diagnosis of recurrent urothelial carcinoma was rendered. The FNA in this case spared the patient an open biopsy. Conclusion: Mass lesions arising in the perineum of patients who underwent cystectomy for urothelial carcinoma should raise the suspicion of urothelial carcinoma recurrence. Evaluation of perineal masses for recurrence of urothelial carcinoma can be made on FNA without the need for open biopsy.

AB - Background: Recurrence of urothelial (transitional cell) carcinoma in the urethra after cystectomy for invasive urothelial carcinoma is relatively uncommon. It is also uncommon for the recurring urethral tumor to present as a painful perineal mass. Fine needle aspiration (FNA) can be used to evaluate such perineal lesions and confirm tumor recurrence. Case: A 5-cm-diameter mass was found in the perineum of a 63-year-old man 1 year after radical cystoprostatectomy for invasive urothelial carcinoma of the urinary bladder. The mass was detected on pelvic computed tomographic scanning. FNA cytology showed numerous urothelial carcinoma cells of high grade displaying squamous cell differentiation mimicking the histopathologic findings of the primary tumor found on cystectomy. Diagnosis of recurrent urothelial carcinoma was rendered. The FNA in this case spared the patient an open biopsy. Conclusion: Mass lesions arising in the perineum of patients who underwent cystectomy for urothelial carcinoma should raise the suspicion of urothelial carcinoma recurrence. Evaluation of perineal masses for recurrence of urothelial carcinoma can be made on FNA without the need for open biopsy.

KW - Aspiration cytology, fine-needle

KW - Carcinoma, urothelial

UR - http://www.scopus.com/inward/record.url?scp=38549087929&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=38549087929&partnerID=8YFLogxK

M3 - Article

C2 - 18323283

AN - SCOPUS:38549087929

VL - 52

SP - 94

EP - 98

JO - Acta Cytologica

JF - Acta Cytologica

SN - 0001-5547

IS - 1

ER -