Filament-directed intercellular contacts during differentiation of cultured chick myoblasts

Robert H. Singer, Jeffrey A. Pudney

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Detergent-extracted, critical point dried chicken myoblasts at early stages of development in tissue culture were observed by electron microscopy. It was found that the organization of filaments within these cells changes significantly during development. A particular specialization of the cellular filament framework is the formation of microprocesses; long extensions of the cellular filament system. These microprocesses appear to be involved in cell-to-cell contact. The filaments of these processes appear to integrate with the filament system of a contacted cell, and possibly transmit tension from one cell to another. The role of these structures in effecting muscle differentiation by forming cytoplasmic connections and the implications for muscle gene expression are discussed.

Original languageEnglish (US)
Pages (from-to)17-29
Number of pages13
JournalTissue and Cell
Volume16
Issue number1
DOIs
StatePublished - 1984
Externally publishedYes

Keywords

  • cell interaction
  • cytoskeleton
  • microfilaments
  • muscle

ASJC Scopus subject areas

  • Developmental Biology
  • Cell Biology

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