Fetal adrenoleukodystrophy: The significance of pathologic lesions in adrenal gland and testis

James M. Powers, Hugo W. Moser, Ann B. Moser, Herbert H. Schaumburg

Research output: Contribution to journalArticlepeer-review

43 Scopus citations

Abstract

Fetal tissues from two abortuses with maternal family histories of adrenoleukodystrophy and with abnormal fatty acids in cultured amniotic fluid cells were examined by light and electron microscopy. Striations and lamellae pathognomonic of adrenoleukodystrophy were found in fetal-zone adrenocortical and Leydig cells. Their significance and differentiation from other lamellar inclusions in adrenoleukodystrophy are discussed.

Original languageEnglish (US)
Pages (from-to)1013-1019
Number of pages7
JournalHuman Pathology
Volume13
Issue number11
DOIs
StatePublished - Nov 1982
Externally publishedYes

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

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