False positivity of FDG-PET/CT in a child with Hodgkin disease

Dildar Bahar Beker; Su Gulsun Berrak; Cengiz Canpolat; Halil Tugtepe; Tunc Ones; Tulay Tecimer

doi:10.1002/pbc.21197

False positivity of FDG-PET/CT in a child with Hodgkin disease

Dildar Bahar Beker, Su Gulsun Berrak, Cengiz Canpolat, Halil Tugtepe, Tunc Ones, Tulay Tecimer

Research output: Contribution to journal › Article › peer-review

10 Scopus citations

Abstract

Role of Positron Emission Tomography (PET) with F-18-2-fluoro-2-deoxy-D- glucose (FDG) in staging of Hodgkin disease is well established despite several controversies. We report a Stage III Hodgkin lymphoma patient with false positive FDG-PET/CT results. Seven-year-old male with Hodgkin lymphoma was in remission at end of chemotherapy. At third and fourth months of postchemotherapy follow-up, increased gallium uptake and positive FDG-PET/CT in right lower quadrant of abdomen was observed. Open biopsy revealed lymphoid hyperplasia. He has been followed for 21 months without any evidence of disease. Despite its documented benefit, we believe that results of FDG-PET/CT should be interpreted with great caution in order to avoid unnecessary interventions.

Original language	English (US)
Pages (from-to)	881-883
Number of pages	3
Journal	Pediatric Blood and Cancer
Volume	50
Issue number	4
DOIs	https://doi.org/10.1002/pbc.21197
State	Published - Apr 2008
Externally published	Yes

Keywords

FDG-PET/CT
False positivity
Hodgkin
Lymphoma

ASJC Scopus subject areas

Pediatrics, Perinatology, and Child Health
Hematology
Oncology

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10.1002/pbc.21197

Cite this

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title = "False positivity of FDG-PET/CT in a child with Hodgkin disease",

abstract = "Role of Positron Emission Tomography (PET) with F-18-2-fluoro-2-deoxy-D- glucose (FDG) in staging of Hodgkin disease is well established despite several controversies. We report a Stage III Hodgkin lymphoma patient with false positive FDG-PET/CT results. Seven-year-old male with Hodgkin lymphoma was in remission at end of chemotherapy. At third and fourth months of postchemotherapy follow-up, increased gallium uptake and positive FDG-PET/CT in right lower quadrant of abdomen was observed. Open biopsy revealed lymphoid hyperplasia. He has been followed for 21 months without any evidence of disease. Despite its documented benefit, we believe that results of FDG-PET/CT should be interpreted with great caution in order to avoid unnecessary interventions.",

keywords = "FDG-PET/CT, False positivity, Hodgkin, Lymphoma",

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AU - Beker, Dildar Bahar

AU - Berrak, Su Gulsun

AU - Canpolat, Cengiz

AU - Tugtepe, Halil

AU - Ones, Tunc

AU - Tecimer, Tulay

PY - 2008/4

Y1 - 2008/4

N2 - Role of Positron Emission Tomography (PET) with F-18-2-fluoro-2-deoxy-D- glucose (FDG) in staging of Hodgkin disease is well established despite several controversies. We report a Stage III Hodgkin lymphoma patient with false positive FDG-PET/CT results. Seven-year-old male with Hodgkin lymphoma was in remission at end of chemotherapy. At third and fourth months of postchemotherapy follow-up, increased gallium uptake and positive FDG-PET/CT in right lower quadrant of abdomen was observed. Open biopsy revealed lymphoid hyperplasia. He has been followed for 21 months without any evidence of disease. Despite its documented benefit, we believe that results of FDG-PET/CT should be interpreted with great caution in order to avoid unnecessary interventions.

AB - Role of Positron Emission Tomography (PET) with F-18-2-fluoro-2-deoxy-D- glucose (FDG) in staging of Hodgkin disease is well established despite several controversies. We report a Stage III Hodgkin lymphoma patient with false positive FDG-PET/CT results. Seven-year-old male with Hodgkin lymphoma was in remission at end of chemotherapy. At third and fourth months of postchemotherapy follow-up, increased gallium uptake and positive FDG-PET/CT in right lower quadrant of abdomen was observed. Open biopsy revealed lymphoid hyperplasia. He has been followed for 21 months without any evidence of disease. Despite its documented benefit, we believe that results of FDG-PET/CT should be interpreted with great caution in order to avoid unnecessary interventions.

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KW - Lymphoma

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False positivity of FDG-PET/CT in a child with Hodgkin disease

Abstract

Keywords

ASJC Scopus subject areas

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