Factor analysis of repetitive behaviors in autism as measured by the Y-BOCS

Evdokia Anagnostou, William Chaplin, Dryden Watner, Jeremy M. Silverman, Christopher J. Smith, Karen Zagursky, Lauren A. Kryzak, Thomas E. Corwin, Nicole Feirsen, Nadia Tanel, Eric Hollander

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

The authors carried out a factor analysis of the Yale-Brown Obsessive-Compulsive Scale checklist at the category level in order to reduce the number of variables in this domain and ultimately identify possible endophenotypes; 181 children with autism were enrolled. The authors estimated a tetrachoric correlation matrix among the dichotomous symptom categories and then used exploratory and confirmatory factor analyses to identify a clinically meaningful factor structure for this correlation matrix. Their analysis supported a four-factor solution: obsessions, higher-order repetitive behaviors, lower-order repetitive behaviors, and hoarding. These findings are another step in the effort to identify genetically and biologically distinct groups within this population.

Original languageEnglish (US)
Pages (from-to)332-339
Number of pages8
JournalJournal of Neuropsychiatry and Clinical Neurosciences
Volume23
Issue number3
DOIs
StatePublished - 2011

Fingerprint

Autistic Disorder
Statistical Factor Analysis
Endophenotypes
Obsessive Behavior
Checklist
Population Groups
Hoarding

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • Clinical Neurology

Cite this

Factor analysis of repetitive behaviors in autism as measured by the Y-BOCS. / Anagnostou, Evdokia; Chaplin, William; Watner, Dryden; Silverman, Jeremy M.; Smith, Christopher J.; Zagursky, Karen; Kryzak, Lauren A.; Corwin, Thomas E.; Feirsen, Nicole; Tanel, Nadia; Hollander, Eric.

In: Journal of Neuropsychiatry and Clinical Neurosciences, Vol. 23, No. 3, 2011, p. 332-339.

Research output: Contribution to journalArticle

Anagnostou, E, Chaplin, W, Watner, D, Silverman, JM, Smith, CJ, Zagursky, K, Kryzak, LA, Corwin, TE, Feirsen, N, Tanel, N & Hollander, E 2011, 'Factor analysis of repetitive behaviors in autism as measured by the Y-BOCS', Journal of Neuropsychiatry and Clinical Neurosciences, vol. 23, no. 3, pp. 332-339. https://doi.org/10.1176/appi.neuropsych.23.3.332
Anagnostou, Evdokia ; Chaplin, William ; Watner, Dryden ; Silverman, Jeremy M. ; Smith, Christopher J. ; Zagursky, Karen ; Kryzak, Lauren A. ; Corwin, Thomas E. ; Feirsen, Nicole ; Tanel, Nadia ; Hollander, Eric. / Factor analysis of repetitive behaviors in autism as measured by the Y-BOCS. In: Journal of Neuropsychiatry and Clinical Neurosciences. 2011 ; Vol. 23, No. 3. pp. 332-339.
@article{210a65cf95f8467498fcb0b66f3c6355,
title = "Factor analysis of repetitive behaviors in autism as measured by the Y-BOCS",
abstract = "The authors carried out a factor analysis of the Yale-Brown Obsessive-Compulsive Scale checklist at the category level in order to reduce the number of variables in this domain and ultimately identify possible endophenotypes; 181 children with autism were enrolled. The authors estimated a tetrachoric correlation matrix among the dichotomous symptom categories and then used exploratory and confirmatory factor analyses to identify a clinically meaningful factor structure for this correlation matrix. Their analysis supported a four-factor solution: obsessions, higher-order repetitive behaviors, lower-order repetitive behaviors, and hoarding. These findings are another step in the effort to identify genetically and biologically distinct groups within this population.",
author = "Evdokia Anagnostou and William Chaplin and Dryden Watner and Silverman, {Jeremy M.} and Smith, {Christopher J.} and Karen Zagursky and Kryzak, {Lauren A.} and Corwin, {Thomas E.} and Nicole Feirsen and Nadia Tanel and Eric Hollander",
year = "2011",
doi = "10.1176/appi.neuropsych.23.3.332",
language = "English (US)",
volume = "23",
pages = "332--339",
journal = "Journal of Neuropsychiatry and Clinical Neurosciences",
issn = "0895-0172",
publisher = "American Psychiatric Publishing Inc.",
number = "3",

}

TY - JOUR

T1 - Factor analysis of repetitive behaviors in autism as measured by the Y-BOCS

AU - Anagnostou, Evdokia

AU - Chaplin, William

AU - Watner, Dryden

AU - Silverman, Jeremy M.

AU - Smith, Christopher J.

AU - Zagursky, Karen

AU - Kryzak, Lauren A.

AU - Corwin, Thomas E.

AU - Feirsen, Nicole

AU - Tanel, Nadia

AU - Hollander, Eric

PY - 2011

Y1 - 2011

N2 - The authors carried out a factor analysis of the Yale-Brown Obsessive-Compulsive Scale checklist at the category level in order to reduce the number of variables in this domain and ultimately identify possible endophenotypes; 181 children with autism were enrolled. The authors estimated a tetrachoric correlation matrix among the dichotomous symptom categories and then used exploratory and confirmatory factor analyses to identify a clinically meaningful factor structure for this correlation matrix. Their analysis supported a four-factor solution: obsessions, higher-order repetitive behaviors, lower-order repetitive behaviors, and hoarding. These findings are another step in the effort to identify genetically and biologically distinct groups within this population.

AB - The authors carried out a factor analysis of the Yale-Brown Obsessive-Compulsive Scale checklist at the category level in order to reduce the number of variables in this domain and ultimately identify possible endophenotypes; 181 children with autism were enrolled. The authors estimated a tetrachoric correlation matrix among the dichotomous symptom categories and then used exploratory and confirmatory factor analyses to identify a clinically meaningful factor structure for this correlation matrix. Their analysis supported a four-factor solution: obsessions, higher-order repetitive behaviors, lower-order repetitive behaviors, and hoarding. These findings are another step in the effort to identify genetically and biologically distinct groups within this population.

UR - http://www.scopus.com/inward/record.url?scp=80054967579&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=80054967579&partnerID=8YFLogxK

U2 - 10.1176/appi.neuropsych.23.3.332

DO - 10.1176/appi.neuropsych.23.3.332

M3 - Article

VL - 23

SP - 332

EP - 339

JO - Journal of Neuropsychiatry and Clinical Neurosciences

JF - Journal of Neuropsychiatry and Clinical Neurosciences

SN - 0895-0172

IS - 3

ER -