Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to legionella: 10 year experience

Moronke A. Noah, Geethanjali Ramachandra, Margaret M. Hickey, David R. Jenkins, Chris J. Harvey, Claire A. Westrope, Richard K. Firmin, Giles J. Peek

Research output: Contribution to journalReview article

9 Citations (Scopus)

Abstract

Legionella-associated respiratory failure has a high mortality, despite modern ventilation modalities. Extracorporeal membrane oxygenation (ECMO) is used to achieve gas exchange independent of pulmonary function in patients with severe respiratory failure. This was a retrospective review of the management and outcome of patients with Legionella-associated respiratory failure treated with ECMO support in a large ECMO center over the past 10 years. A retrospective review of patients with confirmed Legionella-associated severe respiratory failure managed with ECMO support at a single center. Between 2000 and 2010, 19 patients with severe respiratory failure caused by Legionella were managed with ECMO after failure to respond to conventional intensive care management. Median PaO2/FiO2 ratio was 66 and median pCO2 was 60 torr. Sixteen patients (84%) survived to hospital discharge. Extracorporeal membrane oxygenation should be considered in patients with Legionella-associated respiratory failure, who have failed conventional ventilation.

Original languageEnglish (US)
Pages (from-to)328-330
Number of pages3
JournalASAIO Journal
Volume59
Issue number3
DOIs
StatePublished - May 2013
Externally publishedYes

Fingerprint

Legionella
Extracorporeal Membrane Oxygenation
Oxygenation
Respiratory Insufficiency
Membranes
Ventilation
Pulmonary Gas Exchange
Critical Care
Gases
Mortality

Keywords

  • extracorporeal membrane oxygenation
  • Legionella
  • Legionnaire's disease
  • severe respiratory failure

ASJC Scopus subject areas

  • Biophysics
  • Biomaterials
  • Bioengineering
  • Biomedical Engineering
  • Medicine(all)

Cite this

Noah, M. A., Ramachandra, G., Hickey, M. M., Jenkins, D. R., Harvey, C. J., Westrope, C. A., ... Peek, G. J. (2013). Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to legionella: 10 year experience. ASAIO Journal, 59(3), 328-330. https://doi.org/10.1097/MAT.0b013e31829119c6

Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to legionella : 10 year experience. / Noah, Moronke A.; Ramachandra, Geethanjali; Hickey, Margaret M.; Jenkins, David R.; Harvey, Chris J.; Westrope, Claire A.; Firmin, Richard K.; Peek, Giles J.

In: ASAIO Journal, Vol. 59, No. 3, 05.2013, p. 328-330.

Research output: Contribution to journalReview article

Noah, MA, Ramachandra, G, Hickey, MM, Jenkins, DR, Harvey, CJ, Westrope, CA, Firmin, RK & Peek, GJ 2013, 'Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to legionella: 10 year experience', ASAIO Journal, vol. 59, no. 3, pp. 328-330. https://doi.org/10.1097/MAT.0b013e31829119c6
Noah, Moronke A. ; Ramachandra, Geethanjali ; Hickey, Margaret M. ; Jenkins, David R. ; Harvey, Chris J. ; Westrope, Claire A. ; Firmin, Richard K. ; Peek, Giles J. / Extracorporeal membrane oxygenation and severe acute respiratory distress secondary to legionella : 10 year experience. In: ASAIO Journal. 2013 ; Vol. 59, No. 3. pp. 328-330.
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