Evolution and sequence analysis of a human Y-chromosomal DNA fragment

E. C. Whisenant, B. K.A. Rasheed, H. Ostrer, Y. M. Bhatnagar

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middle euchromatic portion of the long arm of the human Y chromosome at Yq11.2. Sequence analysis revealed the presence of an atypical Alu element and two regions rich in polypyrimidine-polypurine residues.

Original languageEnglish (US)
Pages (from-to)133-141
Number of pages9
JournalJournal of Molecular Evolution
Volume33
Issue number2
DOIs
StatePublished - Aug 1 1991
Externally publishedYes

Keywords

  • Alu element
  • DNA
  • Evolution
  • Human
  • PUPPY sequence
  • Primate
  • Y-chromosome

ASJC Scopus subject areas

  • Ecology, Evolution, Behavior and Systematics
  • Molecular Biology
  • Genetics

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