Evolution and sequence analysis of a human Y-chromosomal DNA fragment

E. C. Whisenant, B. K A Rasheed, Harry Ostrer, Y. M. Bhatnagar

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

A Y-chromosomal DNA fragment has been isolated from a human Y-Charon 21A recombinant library. Evolutionary analysis of 1F5 indicates that the size and sequence of this fragment have been conserved in higher primates. Deletion mapping and in situ hybridization analysis have localized 1F5 to the middle euchromatic portion of the long arm of the human Y chromosome at Yq11.2. Sequence analysis revealed the presence of an atypical Alu element and two regions rich in polypyrimidine-polypurine residues.

Original languageEnglish (US)
Pages (from-to)133-141
Number of pages9
JournalJournal of Molecular Evolution
Volume33
Issue number2
DOIs
StatePublished - Aug 1991
Externally publishedYes

Fingerprint

Pluto
Chromosomes, Human, Y
Alu Elements
Chromosomes
Primates
In Situ Hybridization
Sequence Analysis
sequence analysis
DNA
Y chromosome
in situ hybridization
chromosome mapping
primate
chromosome
analysis

Keywords

  • Alu element
  • DNA
  • Evolution
  • Human
  • Primate
  • PUPPY sequence
  • Y-chromosome

ASJC Scopus subject areas

  • Genetics(clinical)
  • Molecular Biology
  • Genetics
  • Biochemistry
  • Biochemistry, Genetics and Molecular Biology(all)
  • Ecology, Evolution, Behavior and Systematics
  • Agricultural and Biological Sciences (miscellaneous)
  • Agricultural and Biological Sciences(all)

Cite this

Evolution and sequence analysis of a human Y-chromosomal DNA fragment. / Whisenant, E. C.; Rasheed, B. K A; Ostrer, Harry; Bhatnagar, Y. M.

In: Journal of Molecular Evolution, Vol. 33, No. 2, 08.1991, p. 133-141.

Research output: Contribution to journalArticle

Whisenant, E. C. ; Rasheed, B. K A ; Ostrer, Harry ; Bhatnagar, Y. M. / Evolution and sequence analysis of a human Y-chromosomal DNA fragment. In: Journal of Molecular Evolution. 1991 ; Vol. 33, No. 2. pp. 133-141.
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