TY - JOUR
T1 - Evidence for biliary excretion of vancomycin into stool during intravenous therapy
T2 - Potential implications for rectal colonization with vancomycin-resistant enterococci
AU - Currie, Brian P.
AU - Lemos-Filho, Luciano
PY - 2004/11
Y1 - 2004/11
N2 - Sixty-three stool samples and five bile samples were prospectively collected from 33 patients receiving intravenous vancomycin therapy and were quantitatively analyzed for vancomycin by a competitive immuno-assay. Vancomycin was excreted via bile into the stools of almost all patients at concentrations of 3.3 to 94.8 μg/ml after ≥5 days of a therapy of 1 g every 12 h.
AB - Sixty-three stool samples and five bile samples were prospectively collected from 33 patients receiving intravenous vancomycin therapy and were quantitatively analyzed for vancomycin by a competitive immuno-assay. Vancomycin was excreted via bile into the stools of almost all patients at concentrations of 3.3 to 94.8 μg/ml after ≥5 days of a therapy of 1 g every 12 h.
UR - http://www.scopus.com/inward/record.url?scp=7244260429&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=7244260429&partnerID=8YFLogxK
U2 - 10.1128/AAC.48.11.4427-4429.2004
DO - 10.1128/AAC.48.11.4427-4429.2004
M3 - Article
C2 - 15504873
AN - SCOPUS:7244260429
SN - 0066-4804
VL - 48
SP - 4427
EP - 4429
JO - Antimicrobial Agents and Chemotherapy
JF - Antimicrobial Agents and Chemotherapy
IS - 11
ER -
