Etiology of adolescent idiopathic scoliosis: A literature review

Sina Rashidi Kikanloo; Sandip Parshottam Tarpada; Woojin Cho

doi:10.31616/asj.2018.0096

Etiology of adolescent idiopathic scoliosis: A literature review

Sina Rashidi Kikanloo, Sandip Parshottam Tarpada, Woojin Cho

Orthopaedic Surgery

Research output: Contribution to journal › Article › peer-review

55 Scopus citations

Abstract

Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.

Original language	English (US)
Pages (from-to)	519-526
Number of pages	8
Journal	Asian Spine Journal
Volume	13
Issue number	3
DOIs	https://doi.org/10.31616/asj.2018.0096
State	Published - Jun 1 2019

Keywords

Adolescent
Adolescent idiopathic scoliosis
Cobb angle
Etiology
Review
Scoliosis

ASJC Scopus subject areas

Surgery
Orthopedics and Sports Medicine

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10.31616/asj.2018.0096

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title = "Etiology of adolescent idiopathic scoliosis: A literature review",

abstract = "Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.",

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AB - Adolescent idiopathic scoliosis (AIS) is the peripubertal development of spinal curvature of a minimum of 10°. AIS is thought to be attributable to genetic factors, nutrition, early exposure to toxins, and hormonal dysregulation. Recent literature suggests these factors may compound to determine both disease onset and severity. Currently, treatment is limited to observation, bracing, and surgical intervention. Intervention is presently determined by severity and risk of curve progression. As they emerge, new therapies may target specific etiologies of AIS.

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KW - Cobb angle

KW - Etiology

KW - Review

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Etiology of adolescent idiopathic scoliosis: A literature review

Abstract

Keywords

ASJC Scopus subject areas

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