Erythropoiesis-stimulating agents for anemia in older adults

Research output: Contribution to journalArticle

Abstract

Erythropoietin, a humoral factor produced predominantly in the kidney, stimulates red blood cell production in the bone marrow. Erythropoiesis-stimulating agents (ESAs) have been used for years in the treatment of anemia, with extensive experience and benefits in anemia of chronic kidney disease. Recent data have suggested adverse consequences with use of ESAs, perhaps relating to inappropriate use, and prompting release of guidelines to ensure safe use and maximize benefit. When prescribing ESAs, indications, requirements to monitor laboratory parameters (hemoglobin levels and ferrokinetics), and clinical status need to be stringently followed.

Original languageEnglish (US)
Pages (from-to)297-303
Number of pages7
JournalFormulary
Volume43
Issue number8
StatePublished - Aug 2008
Externally publishedYes

Fingerprint

Hematinics
Anemia
Erythropoietin
Chronic Renal Insufficiency
Hemoglobins
Erythrocytes
Bone Marrow
Guidelines
Kidney

ASJC Scopus subject areas

  • Pharmacology (medical)

Cite this

Erythropoiesis-stimulating agents for anemia in older adults. / Dharmarajan, Thiruvinvamalai S.; Widjaja, David.

In: Formulary, Vol. 43, No. 8, 08.2008, p. 297-303.

Research output: Contribution to journalArticle

@article{f3212025caa742289bff9cc900193b84,
title = "Erythropoiesis-stimulating agents for anemia in older adults",
abstract = "Erythropoietin, a humoral factor produced predominantly in the kidney, stimulates red blood cell production in the bone marrow. Erythropoiesis-stimulating agents (ESAs) have been used for years in the treatment of anemia, with extensive experience and benefits in anemia of chronic kidney disease. Recent data have suggested adverse consequences with use of ESAs, perhaps relating to inappropriate use, and prompting release of guidelines to ensure safe use and maximize benefit. When prescribing ESAs, indications, requirements to monitor laboratory parameters (hemoglobin levels and ferrokinetics), and clinical status need to be stringently followed.",
author = "Dharmarajan, {Thiruvinvamalai S.} and David Widjaja",
year = "2008",
month = "8",
language = "English (US)",
volume = "43",
pages = "297--303",
journal = "Formulary",
issn = "1082-801X",
publisher = "Advanstar Communications",
number = "8",

}

TY - JOUR

T1 - Erythropoiesis-stimulating agents for anemia in older adults

AU - Dharmarajan, Thiruvinvamalai S.

AU - Widjaja, David

PY - 2008/8

Y1 - 2008/8

N2 - Erythropoietin, a humoral factor produced predominantly in the kidney, stimulates red blood cell production in the bone marrow. Erythropoiesis-stimulating agents (ESAs) have been used for years in the treatment of anemia, with extensive experience and benefits in anemia of chronic kidney disease. Recent data have suggested adverse consequences with use of ESAs, perhaps relating to inappropriate use, and prompting release of guidelines to ensure safe use and maximize benefit. When prescribing ESAs, indications, requirements to monitor laboratory parameters (hemoglobin levels and ferrokinetics), and clinical status need to be stringently followed.

AB - Erythropoietin, a humoral factor produced predominantly in the kidney, stimulates red blood cell production in the bone marrow. Erythropoiesis-stimulating agents (ESAs) have been used for years in the treatment of anemia, with extensive experience and benefits in anemia of chronic kidney disease. Recent data have suggested adverse consequences with use of ESAs, perhaps relating to inappropriate use, and prompting release of guidelines to ensure safe use and maximize benefit. When prescribing ESAs, indications, requirements to monitor laboratory parameters (hemoglobin levels and ferrokinetics), and clinical status need to be stringently followed.

UR - http://www.scopus.com/inward/record.url?scp=52149089679&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=52149089679&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:52149089679

VL - 43

SP - 297

EP - 303

JO - Formulary

JF - Formulary

SN - 1082-801X

IS - 8

ER -