Epithelial trafficking: New routes to familiar places

Enrique Rodriguez-Boulan, Anne Müsch, Andre Le Bivic

Research output: Contribution to journalReview article

41 Scopus citations

Abstract

Research carried out in mammalian epithelial cell systems over the past 25 years has delineated pathways and sorting signals involved in polarized delivery of plasma membrane proteins. Recently some progress has been made in the identification of mechanisms underlying this polarized trafficking and in the visualization of trafficking routes in live cells. A promising area of research is the study of trafficking functions of novel polarity genes identified in Drosophila and Caenorhabditis elegans.

Original languageEnglish (US)
Pages (from-to)436-442
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume16
Issue number4
DOIs
StatePublished - Aug 1 2004
Externally publishedYes

Keywords

  • ARE
  • FRAP
  • GFP
  • GPI
  • HA
  • LDLR
  • LGL
  • MDCK
  • apical recycling endosome
  • fluorescence recovery after photobleaching
  • glycosylphosphatidylinositol
  • green fluorescent protein
  • hemagglutinin
  • lethal giant larvae
  • low-density lipoprotein receptor

ASJC Scopus subject areas

  • Cell Biology

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