Epithelial trafficking

New routes to familiar places

Enrique Rodriguez-Boulan, Anne Muesch, Andre Le Bivic

Research output: Contribution to journalArticle

40 Citations (Scopus)

Abstract

Research carried out in mammalian epithelial cell systems over the past 25 years has delineated pathways and sorting signals involved in polarized delivery of plasma membrane proteins. Recently some progress has been made in the identification of mechanisms underlying this polarized trafficking and in the visualization of trafficking routes in live cells. A promising area of research is the study of trafficking functions of novel polarity genes identified in Drosophila and Caenorhabditis elegans.

Original languageEnglish (US)
Pages (from-to)436-442
Number of pages7
JournalCurrent Opinion in Cell Biology
Volume16
Issue number4
DOIs
StatePublished - Aug 2004
Externally publishedYes

Fingerprint

Caenorhabditis elegans
Research
Drosophila
Blood Proteins
Signal Transduction
Membrane Proteins
Epithelial Cells
Cell Membrane
Genes

Keywords

  • apical recycling endosome
  • ARE
  • fluorescence recovery after photobleaching
  • FRAP
  • GFP
  • glycosylphosphatidylinositol
  • GPI
  • green fluorescent protein
  • HA
  • hemagglutinin
  • LDLR
  • lethal giant larvae
  • LGL
  • low-density lipoprotein receptor
  • MDCK

ASJC Scopus subject areas

  • Cell Biology

Cite this

Epithelial trafficking : New routes to familiar places. / Rodriguez-Boulan, Enrique; Muesch, Anne; Le Bivic, Andre.

In: Current Opinion in Cell Biology, Vol. 16, No. 4, 08.2004, p. 436-442.

Research output: Contribution to journalArticle

Rodriguez-Boulan, Enrique ; Muesch, Anne ; Le Bivic, Andre. / Epithelial trafficking : New routes to familiar places. In: Current Opinion in Cell Biology. 2004 ; Vol. 16, No. 4. pp. 436-442.
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