Enzymic synthesis of deoxyribonucleic acid: XX. Electron microscopy of products primed by native templates

R. B. Inman, C. L. Schildkraut, Arthur Kornberg

Research output: Contribution to journalArticle

20 Scopus citations

Abstract

Native T7 DNA is seen in the electron microscope as a continuous fiber about 11 μ, long, without branches. The product of replication of T7 DNA (and also phage λ DNA) by Escherichia coli polymerase showed, in a large number of the molecules, a branched structure with as many as 12 ends. Branching appears early in the course of replication and persists in the product isolated free from template and enzyme.

Original languageEnglish (US)
Pages (from-to)285-292
Number of pages8
JournalJournal of Molecular Biology
Volume11
Issue number2
DOIs
StatePublished - Jan 1 1965
Externally publishedYes

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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