TY - JOUR
T1 - Enzymic synthesis of deoxyribonucleic acid
T2 - XX. Electron microscopy of products primed by native templates
AU - Inman, R. B.
AU - Schildkraut, C. L.
AU - Kornberg, Arthur
PY - 1965
Y1 - 1965
N2 - Native T7 DNA is seen in the electron microscope as a continuous fiber about 11 μ, long, without branches. The product of replication of T7 DNA (and also phage λ DNA) by Escherichia coli polymerase showed, in a large number of the molecules, a branched structure with as many as 12 ends. Branching appears early in the course of replication and persists in the product isolated free from template and enzyme.
AB - Native T7 DNA is seen in the electron microscope as a continuous fiber about 11 μ, long, without branches. The product of replication of T7 DNA (and also phage λ DNA) by Escherichia coli polymerase showed, in a large number of the molecules, a branched structure with as many as 12 ends. Branching appears early in the course of replication and persists in the product isolated free from template and enzyme.
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U2 - 10.1016/S0022-2836(65)80058-4
DO - 10.1016/S0022-2836(65)80058-4
M3 - Article
C2 - 14290346
AN - SCOPUS:11144272980
SN - 0022-2836
VL - 11
SP - 285
EP - 292
JO - Journal of Molecular Biology
JF - Journal of Molecular Biology
IS - 2
ER -