Endolumenal fundoplication with esophyX: The initial North American experience

Simon Bergman, Dean J. Mikami, Jeffrey W. Hazey, Jason C. Roland, Rebecca Dettorre, Scott W. Melvin

Research output: Contribution to journalArticle

18 Scopus citations


EsophyX is a novel endolumenal therapeutic option for the treatment of gastroesophageal reflux disease (GERD). The device is passed into the stomach, where it deploys a series of full-thickness fasteners to create a neogastroesophageal valve. The objective of this study was to demonstrate the safety and characterize the effectiveness of this approach in the initial North American experience. This is a retrospective study of consecutive patients with GERD who had undergone endolumenal fundoplication with the EsophyX device. At follow-up, proton pump inhibitor usage was elicited and 2 validated questionnaires were administered measuring GERD health-related quality of life (range 0-50) and symptom severity (range 0-72). In limited preliminary evaluation, the initial North American experience with endolumenal fundoplication using the EsophyX device is that it appears to be safe and provides moderate effectiveness in treating the symptoms of GERD. Further studies comparing this technique with conventional medical and surgical therapies are necessary.

Original languageEnglish (US)
Pages (from-to)166-170
Number of pages5
JournalSurgical Innovation
Issue number3
StatePublished - Aug 26 2008
Externally publishedYes


  • Endolumenal fundoplication
  • EsophyX
  • GERD

ASJC Scopus subject areas

  • Surgery

Fingerprint Dive into the research topics of 'Endolumenal fundoplication with esophyX: The initial North American experience'. Together they form a unique fingerprint.

  • Cite this