Endolumenal fundoplication with esophyX

The initial North American experience

Simon Bergman, Dean J. Mikami, Jeffrey W. Hazey, Jason C. Roland, Rebecca Dettorre, W. Scott Melvin

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

EsophyX is a novel endolumenal therapeutic option for the treatment of gastroesophageal reflux disease (GERD). The device is passed into the stomach, where it deploys a series of full-thickness fasteners to create a neogastroesophageal valve. The objective of this study was to demonstrate the safety and characterize the effectiveness of this approach in the initial North American experience. This is a retrospective study of consecutive patients with GERD who had undergone endolumenal fundoplication with the EsophyX device. At follow-up, proton pump inhibitor usage was elicited and 2 validated questionnaires were administered measuring GERD health-related quality of life (range 0-50) and symptom severity (range 0-72). In limited preliminary evaluation, the initial North American experience with endolumenal fundoplication using the EsophyX device is that it appears to be safe and provides moderate effectiveness in treating the symptoms of GERD. Further studies comparing this technique with conventional medical and surgical therapies are necessary.

Original languageEnglish (US)
Pages (from-to)166-170
Number of pages5
JournalSurgical Innovation
Volume15
Issue number3
DOIs
StatePublished - 2008
Externally publishedYes

Fingerprint

Fundoplication
Gastroesophageal Reflux
Equipment and Supplies
Proton Pump Inhibitors
Stomach
Therapeutics
Retrospective Studies
Quality of Life
Safety

Keywords

  • Endolumenal fundoplication
  • EsophyX
  • GERD

ASJC Scopus subject areas

  • Surgery

Cite this

Endolumenal fundoplication with esophyX : The initial North American experience. / Bergman, Simon; Mikami, Dean J.; Hazey, Jeffrey W.; Roland, Jason C.; Dettorre, Rebecca; Melvin, W. Scott.

In: Surgical Innovation, Vol. 15, No. 3, 2008, p. 166-170.

Research output: Contribution to journalArticle

Bergman, S, Mikami, DJ, Hazey, JW, Roland, JC, Dettorre, R & Melvin, WS 2008, 'Endolumenal fundoplication with esophyX: The initial North American experience', Surgical Innovation, vol. 15, no. 3, pp. 166-170. https://doi.org/10.1177/1553350608321588
Bergman, Simon ; Mikami, Dean J. ; Hazey, Jeffrey W. ; Roland, Jason C. ; Dettorre, Rebecca ; Melvin, W. Scott. / Endolumenal fundoplication with esophyX : The initial North American experience. In: Surgical Innovation. 2008 ; Vol. 15, No. 3. pp. 166-170.
@article{43ee73a0090e4941bf1026029f3e3c08,
title = "Endolumenal fundoplication with esophyX: The initial North American experience",
abstract = "EsophyX is a novel endolumenal therapeutic option for the treatment of gastroesophageal reflux disease (GERD). The device is passed into the stomach, where it deploys a series of full-thickness fasteners to create a neogastroesophageal valve. The objective of this study was to demonstrate the safety and characterize the effectiveness of this approach in the initial North American experience. This is a retrospective study of consecutive patients with GERD who had undergone endolumenal fundoplication with the EsophyX device. At follow-up, proton pump inhibitor usage was elicited and 2 validated questionnaires were administered measuring GERD health-related quality of life (range 0-50) and symptom severity (range 0-72). In limited preliminary evaluation, the initial North American experience with endolumenal fundoplication using the EsophyX device is that it appears to be safe and provides moderate effectiveness in treating the symptoms of GERD. Further studies comparing this technique with conventional medical and surgical therapies are necessary.",
keywords = "Endolumenal fundoplication, EsophyX, GERD",
author = "Simon Bergman and Mikami, {Dean J.} and Hazey, {Jeffrey W.} and Roland, {Jason C.} and Rebecca Dettorre and Melvin, {W. Scott}",
year = "2008",
doi = "10.1177/1553350608321588",
language = "English (US)",
volume = "15",
pages = "166--170",
journal = "Surgical Innovation",
issn = "1553-3506",
publisher = "SAGE Publications Inc.",
number = "3",

}

TY - JOUR

T1 - Endolumenal fundoplication with esophyX

T2 - The initial North American experience

AU - Bergman, Simon

AU - Mikami, Dean J.

AU - Hazey, Jeffrey W.

AU - Roland, Jason C.

AU - Dettorre, Rebecca

AU - Melvin, W. Scott

PY - 2008

Y1 - 2008

N2 - EsophyX is a novel endolumenal therapeutic option for the treatment of gastroesophageal reflux disease (GERD). The device is passed into the stomach, where it deploys a series of full-thickness fasteners to create a neogastroesophageal valve. The objective of this study was to demonstrate the safety and characterize the effectiveness of this approach in the initial North American experience. This is a retrospective study of consecutive patients with GERD who had undergone endolumenal fundoplication with the EsophyX device. At follow-up, proton pump inhibitor usage was elicited and 2 validated questionnaires were administered measuring GERD health-related quality of life (range 0-50) and symptom severity (range 0-72). In limited preliminary evaluation, the initial North American experience with endolumenal fundoplication using the EsophyX device is that it appears to be safe and provides moderate effectiveness in treating the symptoms of GERD. Further studies comparing this technique with conventional medical and surgical therapies are necessary.

AB - EsophyX is a novel endolumenal therapeutic option for the treatment of gastroesophageal reflux disease (GERD). The device is passed into the stomach, where it deploys a series of full-thickness fasteners to create a neogastroesophageal valve. The objective of this study was to demonstrate the safety and characterize the effectiveness of this approach in the initial North American experience. This is a retrospective study of consecutive patients with GERD who had undergone endolumenal fundoplication with the EsophyX device. At follow-up, proton pump inhibitor usage was elicited and 2 validated questionnaires were administered measuring GERD health-related quality of life (range 0-50) and symptom severity (range 0-72). In limited preliminary evaluation, the initial North American experience with endolumenal fundoplication using the EsophyX device is that it appears to be safe and provides moderate effectiveness in treating the symptoms of GERD. Further studies comparing this technique with conventional medical and surgical therapies are necessary.

KW - Endolumenal fundoplication

KW - EsophyX

KW - GERD

UR - http://www.scopus.com/inward/record.url?scp=49849096742&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=49849096742&partnerID=8YFLogxK

U2 - 10.1177/1553350608321588

DO - 10.1177/1553350608321588

M3 - Article

VL - 15

SP - 166

EP - 170

JO - Surgical Innovation

JF - Surgical Innovation

SN - 1553-3506

IS - 3

ER -