TY - JOUR
T1 - Endo-rectal balloon cavity dosimetry in a phantom
T2 - Performance under IMRT and helical tomotherapy beams
AU - Hardcastle, Nicholas
AU - Metcalfe, Peter E.
AU - Rosenfeld, Anatoly B.
AU - Tomé, Wolfgang A.
N1 - Funding Information:
The authors would like to thank the Australian Rotary Health Research Fund and the NSW Cancer Institute Clinical Leaders program for funding for this research. Also supported in part by a grant from the National Institute of Health R01CA106835.
PY - 2009/7
Y1 - 2009/7
N2 - Background and purpose: The use of endo-rectal balloons as immobilisation devices in external beam radiotherapy for prostate cancer has led to improved target position reproducibility and a decrease in rectal toxicity. The air cavity created by an endo-rectal balloon in photon radiotherapy perturbs the dose distribution. In this study, the effect of the balloon cavity on the dose distribution and the accuracy to which two treatment planning systems calculate the dose distribution were investigated. Materials and methods: Single beams as well as 3D conformal, conventional IMRT and helical tomotherapy treatment plans were investigated using a specifically constructed phantom. Radiochromic film was used to measure the cavity wall doses and cavity wall DVHs. Results: For a 70 Gy prescription dose both the Pinnacle and TomoTherapy TPSs over-predicted the anterior cavity wall dose by 1.43 Gy, 3.92 Gy and 2.67 Gy for 3D conformal, conventional IMRT and helical tomotherapy, respectively. The posterior cavity wall dose was under-predicted by 2.62 Gy, 2.01 Gy and 4.79 Gy for 3D conformal, conventional IMRT and helical tomotherapy, respectively. An over-prediction by the Pinnacle RTPS of the V50, V60, V65 and V70 values for the cavity wall DVH was measured for the 3D conformal and conventional IMRT cases. These reductions may lead to a less than expected rectal toxicity. The TomoTherapy RTPS under-predicted the V50, V60, V65 and V70 values which may lead to higher rectal toxicity than predicted. Conclusion: Calculation of dose around an air cavity created by an endo-rectal balloon provides a challenge for radiotherapy planning systems. Various electronic disequilibrium situations exist due to the cavity, which can lead to a lower anterior rectal wall and higher posterior rectal wall dose than that calculated by planning systems. This has consequences for comparisons of dose volume constraints between different modalities.
AB - Background and purpose: The use of endo-rectal balloons as immobilisation devices in external beam radiotherapy for prostate cancer has led to improved target position reproducibility and a decrease in rectal toxicity. The air cavity created by an endo-rectal balloon in photon radiotherapy perturbs the dose distribution. In this study, the effect of the balloon cavity on the dose distribution and the accuracy to which two treatment planning systems calculate the dose distribution were investigated. Materials and methods: Single beams as well as 3D conformal, conventional IMRT and helical tomotherapy treatment plans were investigated using a specifically constructed phantom. Radiochromic film was used to measure the cavity wall doses and cavity wall DVHs. Results: For a 70 Gy prescription dose both the Pinnacle and TomoTherapy TPSs over-predicted the anterior cavity wall dose by 1.43 Gy, 3.92 Gy and 2.67 Gy for 3D conformal, conventional IMRT and helical tomotherapy, respectively. The posterior cavity wall dose was under-predicted by 2.62 Gy, 2.01 Gy and 4.79 Gy for 3D conformal, conventional IMRT and helical tomotherapy, respectively. An over-prediction by the Pinnacle RTPS of the V50, V60, V65 and V70 values for the cavity wall DVH was measured for the 3D conformal and conventional IMRT cases. These reductions may lead to a less than expected rectal toxicity. The TomoTherapy RTPS under-predicted the V50, V60, V65 and V70 values which may lead to higher rectal toxicity than predicted. Conclusion: Calculation of dose around an air cavity created by an endo-rectal balloon provides a challenge for radiotherapy planning systems. Various electronic disequilibrium situations exist due to the cavity, which can lead to a lower anterior rectal wall and higher posterior rectal wall dose than that calculated by planning systems. This has consequences for comparisons of dose volume constraints between different modalities.
KW - Cavity
KW - Endo-rectal balloon
KW - IMRT
KW - Radiochromic film
KW - Tomotherapy
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U2 - 10.1016/j.radonc.2009.03.004
DO - 10.1016/j.radonc.2009.03.004
M3 - Article
C2 - 19339071
AN - SCOPUS:66949116612
SN - 0167-8140
VL - 92
SP - 48
EP - 56
JO - Radiotherapy and Oncology
JF - Radiotherapy and Oncology
IS - 1
ER -