Emerging use of nanoparticles for the therapeutic ablation of urologic malignancies

Joshua M. Stern; Jeffrey A. Cadeddu

doi:10.1016/j.urolonc.2007.03.019

Emerging use of nanoparticles for the therapeutic ablation of urologic malignancies

Joshua M. Stern, Jeffrey A. Cadeddu

Research output: Contribution to journal › Review article › peer-review

19 Scopus citations

Abstract

Metal nanoshells are a new class of nanoparticle with highly tunable optical properties. Gold nanoshells (GNS) are particularly suitable for use in the surgical arena as their outer shell is composed of a commonly used reduced inert gold. When activated by near infrared light, GNS can raise surrounding temperatures to levels sufficient for cellular ablation. As such, investigators have established both in vitro and in vivo models to examine the role of GNS as a therapeutic modality for the thermal ablation of solid organ tumors.

Original language	English (US)
Pages (from-to)	93-96
Number of pages	4
Journal	Urologic Oncology: Seminars and Original Investigations
Volume	26
Issue number	1
DOIs	https://doi.org/10.1016/j.urolonc.2007.03.019
State	Published - Jan 2008
Externally published	Yes

Keywords

Gold nanoshells
Laser ablation
Nanoparticles
Prostate cancer

ASJC Scopus subject areas

Oncology
Urology

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.urolonc.2007.03.019

Cite this

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abstract = "Metal nanoshells are a new class of nanoparticle with highly tunable optical properties. Gold nanoshells (GNS) are particularly suitable for use in the surgical arena as their outer shell is composed of a commonly used reduced inert gold. When activated by near infrared light, GNS can raise surrounding temperatures to levels sufficient for cellular ablation. As such, investigators have established both in vitro and in vivo models to examine the role of GNS as a therapeutic modality for the thermal ablation of solid organ tumors.",

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AU - Cadeddu, Jeffrey A.

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AB - Metal nanoshells are a new class of nanoparticle with highly tunable optical properties. Gold nanoshells (GNS) are particularly suitable for use in the surgical arena as their outer shell is composed of a commonly used reduced inert gold. When activated by near infrared light, GNS can raise surrounding temperatures to levels sufficient for cellular ablation. As such, investigators have established both in vitro and in vivo models to examine the role of GNS as a therapeutic modality for the thermal ablation of solid organ tumors.

KW - Gold nanoshells

KW - Laser ablation

KW - Nanoparticles

KW - Prostate cancer

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JF - Urologic Oncology: Seminars and Original Investigations

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Emerging use of nanoparticles for the therapeutic ablation of urologic malignancies

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

Access to Document

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