Efficacy of Multi-Detector Computed Tomography for the Diagnosis of Medullary Sponge Kidney

Geoffrey S. Gaunay, Robert G. Berkenblit, Christian H. Tabib, Jeffrey R. Blitstein, Manoj Patel, David M. Hoenig

Research output: Contribution to journalArticle

Abstract

Objective: To expand the diagnostic armamentarium for medullary sponge kidney (MSK), we evaluate the use of high-resolution multidetector computed tomography (MDCT) for MSK diagnosis and compare to the standard intravenous urography (IVU). Despite a significant prevalence amongst stone formers, diagnosis of this well described condition has declined. IVU, the gold standard in MSK diagnosis, has largely been replaced by CT, which has previously been shown unable to demonstrate signs of MSK. Methods and Materials: Patients with known history of MSK based on IVU underwent limited MDCT urogram. Control group patients, without MSK, also had MDCT urograms performed for other clinically indicated conditions. Studies were scored by board-certified radiologists on a 0-2 scale based on the likelihood of MSK. IVU studies, when available, were similarly graded. Results: MDCT was diagnostic of MSK in 9 out of the 10 patients with known history of MSK. No false positives were present in our series. The one case of MSK not detected on MDCT was graded as a "1" on its respective IVU. Sensitivity and specificity were 90 and 100%, respectively, when compared with IVU. Conclusion: Concordance with IVU findings, despite a small reduction in sensitivity, indicates MDCT to be a suitable, and more readily available replacement for IVU in the diagnosis of MSK.

Original languageEnglish (US)
Pages (from-to)139-143
Number of pages5
JournalCurrent Urology
Volume11
Issue number3
DOIs
StatePublished - Mar 1 2018

Fingerprint

Medullary Sponge Kidney
Urography
Tomography
Multidetector Computed Tomography

Keywords

  • Computed tomography scan
  • Kidney stone
  • Nephrolithiasis
  • Urolithiasis

ASJC Scopus subject areas

  • Reproductive Medicine
  • Oncology
  • Urology

Cite this

Efficacy of Multi-Detector Computed Tomography for the Diagnosis of Medullary Sponge Kidney. / Gaunay, Geoffrey S.; Berkenblit, Robert G.; Tabib, Christian H.; Blitstein, Jeffrey R.; Patel, Manoj; Hoenig, David M.

In: Current Urology, Vol. 11, No. 3, 01.03.2018, p. 139-143.

Research output: Contribution to journalArticle

Gaunay, Geoffrey S. ; Berkenblit, Robert G. ; Tabib, Christian H. ; Blitstein, Jeffrey R. ; Patel, Manoj ; Hoenig, David M. / Efficacy of Multi-Detector Computed Tomography for the Diagnosis of Medullary Sponge Kidney. In: Current Urology. 2018 ; Vol. 11, No. 3. pp. 139-143.
@article{c220819537f64f7e87df9a994d0d3475,
title = "Efficacy of Multi-Detector Computed Tomography for the Diagnosis of Medullary Sponge Kidney",
abstract = "Objective: To expand the diagnostic armamentarium for medullary sponge kidney (MSK), we evaluate the use of high-resolution multidetector computed tomography (MDCT) for MSK diagnosis and compare to the standard intravenous urography (IVU). Despite a significant prevalence amongst stone formers, diagnosis of this well described condition has declined. IVU, the gold standard in MSK diagnosis, has largely been replaced by CT, which has previously been shown unable to demonstrate signs of MSK. Methods and Materials: Patients with known history of MSK based on IVU underwent limited MDCT urogram. Control group patients, without MSK, also had MDCT urograms performed for other clinically indicated conditions. Studies were scored by board-certified radiologists on a 0-2 scale based on the likelihood of MSK. IVU studies, when available, were similarly graded. Results: MDCT was diagnostic of MSK in 9 out of the 10 patients with known history of MSK. No false positives were present in our series. The one case of MSK not detected on MDCT was graded as a {"}1{"} on its respective IVU. Sensitivity and specificity were 90 and 100{\%}, respectively, when compared with IVU. Conclusion: Concordance with IVU findings, despite a small reduction in sensitivity, indicates MDCT to be a suitable, and more readily available replacement for IVU in the diagnosis of MSK.",
keywords = "Computed tomography scan, Kidney stone, Nephrolithiasis, Urolithiasis",
author = "Gaunay, {Geoffrey S.} and Berkenblit, {Robert G.} and Tabib, {Christian H.} and Blitstein, {Jeffrey R.} and Manoj Patel and Hoenig, {David M.}",
year = "2018",
month = "3",
day = "1",
doi = "10.1159/000447208",
language = "English (US)",
volume = "11",
pages = "139--143",
journal = "Current Urology",
issn = "1661-7649",
publisher = "S. Karger AG",
number = "3",

}

TY - JOUR

T1 - Efficacy of Multi-Detector Computed Tomography for the Diagnosis of Medullary Sponge Kidney

AU - Gaunay, Geoffrey S.

AU - Berkenblit, Robert G.

AU - Tabib, Christian H.

AU - Blitstein, Jeffrey R.

AU - Patel, Manoj

AU - Hoenig, David M.

PY - 2018/3/1

Y1 - 2018/3/1

N2 - Objective: To expand the diagnostic armamentarium for medullary sponge kidney (MSK), we evaluate the use of high-resolution multidetector computed tomography (MDCT) for MSK diagnosis and compare to the standard intravenous urography (IVU). Despite a significant prevalence amongst stone formers, diagnosis of this well described condition has declined. IVU, the gold standard in MSK diagnosis, has largely been replaced by CT, which has previously been shown unable to demonstrate signs of MSK. Methods and Materials: Patients with known history of MSK based on IVU underwent limited MDCT urogram. Control group patients, without MSK, also had MDCT urograms performed for other clinically indicated conditions. Studies were scored by board-certified radiologists on a 0-2 scale based on the likelihood of MSK. IVU studies, when available, were similarly graded. Results: MDCT was diagnostic of MSK in 9 out of the 10 patients with known history of MSK. No false positives were present in our series. The one case of MSK not detected on MDCT was graded as a "1" on its respective IVU. Sensitivity and specificity were 90 and 100%, respectively, when compared with IVU. Conclusion: Concordance with IVU findings, despite a small reduction in sensitivity, indicates MDCT to be a suitable, and more readily available replacement for IVU in the diagnosis of MSK.

AB - Objective: To expand the diagnostic armamentarium for medullary sponge kidney (MSK), we evaluate the use of high-resolution multidetector computed tomography (MDCT) for MSK diagnosis and compare to the standard intravenous urography (IVU). Despite a significant prevalence amongst stone formers, diagnosis of this well described condition has declined. IVU, the gold standard in MSK diagnosis, has largely been replaced by CT, which has previously been shown unable to demonstrate signs of MSK. Methods and Materials: Patients with known history of MSK based on IVU underwent limited MDCT urogram. Control group patients, without MSK, also had MDCT urograms performed for other clinically indicated conditions. Studies were scored by board-certified radiologists on a 0-2 scale based on the likelihood of MSK. IVU studies, when available, were similarly graded. Results: MDCT was diagnostic of MSK in 9 out of the 10 patients with known history of MSK. No false positives were present in our series. The one case of MSK not detected on MDCT was graded as a "1" on its respective IVU. Sensitivity and specificity were 90 and 100%, respectively, when compared with IVU. Conclusion: Concordance with IVU findings, despite a small reduction in sensitivity, indicates MDCT to be a suitable, and more readily available replacement for IVU in the diagnosis of MSK.

KW - Computed tomography scan

KW - Kidney stone

KW - Nephrolithiasis

KW - Urolithiasis

UR - http://www.scopus.com/inward/record.url?scp=85044372086&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85044372086&partnerID=8YFLogxK

U2 - 10.1159/000447208

DO - 10.1159/000447208

M3 - Article

VL - 11

SP - 139

EP - 143

JO - Current Urology

JF - Current Urology

SN - 1661-7649

IS - 3

ER -