Efficacy of laser-assisted uvulopalatoplasty

Arthur M. Lauretano, Rohit K. Khosla, Gary Richardson, Jean Matheson, J. Woodrow Weiss, Camille Graham, Marvin P. Fried

Research output: Contribution to journalArticle

45 Citations (Scopus)

Abstract

Background and Objective: Laser-assisted uvulopalatoplasty (LAUP) is being used increasingly as a surgical treatment for snoring and obstructive sleep apnea (OSA). There is limited evidence for the success of LAUP in eliminating OSA. This study assesses the efficacy of LAUP in eliminating snoring and OSA and addresses which patients may be the best candidates for LAUP treatment. Study Design/Materials and Methods: From January 1994 to January 1996, 297 patients were evaluated for snoring, with 190 (64%) exhibiting some degree of OSA documented by a PSG: 41/190 (22%) mild OSA; 33/190 (17%) moderate OSA; 85/190 (45%) severe OSA; 31/190 (16%) severity unknown. Ninety patients (90/297) have undergone LAUP treatment: 58/90 (64%) with OSA and 32/90 (36%) with snoring only. Results: Our results indicate a significant reduction of snoring in patients without OSA, but diminishing success in patients with increasing degrees of OSA. Additionally, LAUP was not efficacious in treating OSA: pre-op respiratory disturbance index (RDI) of 10.8 vs. post-op RDI of 19.5 for mild OSA (P = 0.14); pre-op RDI of 22.9 vs. post-op RDI of 25.4 for moderate OSA (P = 0.43); pre-op RDI of 56.8 vs. post-op RDI of 46.3 (P < 0.05), which is statistically but not clinically significant (i.e., RDI remained in the severe range). Conclusion: We conclude that LAUP is an effective treatment for nonapneic snoring, but does not provide sufficient resolution of OSA, and based on our results, LAUP should be considered as an adjunctive therapy rather than a sole treatment for OSA in most cases.

Original languageEnglish (US)
Pages (from-to)109-116
Number of pages8
JournalLasers in Surgery and Medicine
Volume21
Issue number2
DOIs
StatePublished - 1997
Externally publishedYes

Fingerprint

Obstructive Sleep Apnea
Lasers
Snoring
Therapeutics

Keywords

  • Apnea
  • Apnea index
  • Hypopnea
  • Hypopnea index
  • Nonapneic snoring
  • Obstructive sleep apnea (OSA)
  • Polysomnogram (PSG)
  • Respiratory disturbance index (RDI)
  • Snoring
  • Uvulopalatopharyngoplasty (UPPP)

ASJC Scopus subject areas

  • Surgery

Cite this

Lauretano, A. M., Khosla, R. K., Richardson, G., Matheson, J., Woodrow Weiss, J., Graham, C., & Fried, M. P. (1997). Efficacy of laser-assisted uvulopalatoplasty. Lasers in Surgery and Medicine, 21(2), 109-116. https://doi.org/10.1002/(SICI)1096-9101(1997)21:2<109::AID-LSM1>3.0.CO;2-U

Efficacy of laser-assisted uvulopalatoplasty. / Lauretano, Arthur M.; Khosla, Rohit K.; Richardson, Gary; Matheson, Jean; Woodrow Weiss, J.; Graham, Camille; Fried, Marvin P.

In: Lasers in Surgery and Medicine, Vol. 21, No. 2, 1997, p. 109-116.

Research output: Contribution to journalArticle

Lauretano, AM, Khosla, RK, Richardson, G, Matheson, J, Woodrow Weiss, J, Graham, C & Fried, MP 1997, 'Efficacy of laser-assisted uvulopalatoplasty', Lasers in Surgery and Medicine, vol. 21, no. 2, pp. 109-116. https://doi.org/10.1002/(SICI)1096-9101(1997)21:2<109::AID-LSM1>3.0.CO;2-U
Lauretano AM, Khosla RK, Richardson G, Matheson J, Woodrow Weiss J, Graham C et al. Efficacy of laser-assisted uvulopalatoplasty. Lasers in Surgery and Medicine. 1997;21(2):109-116. https://doi.org/10.1002/(SICI)1096-9101(1997)21:2<109::AID-LSM1>3.0.CO;2-U
Lauretano, Arthur M. ; Khosla, Rohit K. ; Richardson, Gary ; Matheson, Jean ; Woodrow Weiss, J. ; Graham, Camille ; Fried, Marvin P. / Efficacy of laser-assisted uvulopalatoplasty. In: Lasers in Surgery and Medicine. 1997 ; Vol. 21, No. 2. pp. 109-116.
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abstract = "Background and Objective: Laser-assisted uvulopalatoplasty (LAUP) is being used increasingly as a surgical treatment for snoring and obstructive sleep apnea (OSA). There is limited evidence for the success of LAUP in eliminating OSA. This study assesses the efficacy of LAUP in eliminating snoring and OSA and addresses which patients may be the best candidates for LAUP treatment. Study Design/Materials and Methods: From January 1994 to January 1996, 297 patients were evaluated for snoring, with 190 (64{\%}) exhibiting some degree of OSA documented by a PSG: 41/190 (22{\%}) mild OSA; 33/190 (17{\%}) moderate OSA; 85/190 (45{\%}) severe OSA; 31/190 (16{\%}) severity unknown. Ninety patients (90/297) have undergone LAUP treatment: 58/90 (64{\%}) with OSA and 32/90 (36{\%}) with snoring only. Results: Our results indicate a significant reduction of snoring in patients without OSA, but diminishing success in patients with increasing degrees of OSA. Additionally, LAUP was not efficacious in treating OSA: pre-op respiratory disturbance index (RDI) of 10.8 vs. post-op RDI of 19.5 for mild OSA (P = 0.14); pre-op RDI of 22.9 vs. post-op RDI of 25.4 for moderate OSA (P = 0.43); pre-op RDI of 56.8 vs. post-op RDI of 46.3 (P < 0.05), which is statistically but not clinically significant (i.e., RDI remained in the severe range). Conclusion: We conclude that LAUP is an effective treatment for nonapneic snoring, but does not provide sufficient resolution of OSA, and based on our results, LAUP should be considered as an adjunctive therapy rather than a sole treatment for OSA in most cases.",
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AU - Graham, Camille

AU - Fried, Marvin P.

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