Effectively doubling the magnetic field in spin-1/2-spin-1, HSQC, HDQC, coupled HSQC, and coupled HDQC in solution NMR

S. Chandra Shekar, Jonathan M. Backer, Mark E. Girvin

Research output: Contribution to journalArticle

3 Citations (Scopus)

Abstract

Pulse sequences for spin- 1 2 -spin-1 pair heteronuclear single quantum correlation (HSQC), heteronuclear double quantum correlation (HDQC), and coupled-HSQC, and coupled-HDQC NMR spectroscopies are outlined, and experimental realization for a C13 - H2 pair is demonstrated in solution state. In both the coupled versions, conditions for generation of in-phase and antiphase multiplets in either dimension are arrived at. The patterns and the intensity ratios are explained. The double quantum (2Q) experiments confirm doubling of both the shift frequency and the splitting due to coupling (to spin 1 2) of the 2Q coherence emanating from spin 1. The frequency doubling is equivalent to the corresponding single quantum (1Q) coherence at double the magnetic field strength. The coupling doubling, however, is independent of the magnetic field strength and a signature feature of the 2Q coherence. The ramification of the relative relaxation rates of 1Q and 2Q coherences is discussed.

Original languageEnglish (US)
Article number184501
JournalJournal of Chemical Physics
Volume128
Issue number18
DOIs
StatePublished - 2008

Fingerprint

Nuclear magnetic resonance
Magnetic fields
nuclear magnetic resonance
magnetic fields
field strength
Nuclear magnetic resonance spectroscopy
frequency shift
fine structure
signatures
pulses
spectroscopy
Experiments

ASJC Scopus subject areas

  • Atomic and Molecular Physics, and Optics

Cite this

Effectively doubling the magnetic field in spin-1/2-spin-1, HSQC, HDQC, coupled HSQC, and coupled HDQC in solution NMR. / Shekar, S. Chandra; Backer, Jonathan M.; Girvin, Mark E.

In: Journal of Chemical Physics, Vol. 128, No. 18, 184501, 2008.

Research output: Contribution to journalArticle

@article{f120e692754542429b0153d13596eee2,
title = "Effectively doubling the magnetic field in spin-1/2-spin-1, HSQC, HDQC, coupled HSQC, and coupled HDQC in solution NMR",
abstract = "Pulse sequences for spin- 1 2 -spin-1 pair heteronuclear single quantum correlation (HSQC), heteronuclear double quantum correlation (HDQC), and coupled-HSQC, and coupled-HDQC NMR spectroscopies are outlined, and experimental realization for a C13 - H2 pair is demonstrated in solution state. In both the coupled versions, conditions for generation of in-phase and antiphase multiplets in either dimension are arrived at. The patterns and the intensity ratios are explained. The double quantum (2Q) experiments confirm doubling of both the shift frequency and the splitting due to coupling (to spin 1 2) of the 2Q coherence emanating from spin 1. The frequency doubling is equivalent to the corresponding single quantum (1Q) coherence at double the magnetic field strength. The coupling doubling, however, is independent of the magnetic field strength and a signature feature of the 2Q coherence. The ramification of the relative relaxation rates of 1Q and 2Q coherences is discussed.",
author = "Shekar, {S. Chandra} and Backer, {Jonathan M.} and Girvin, {Mark E.}",
year = "2008",
doi = "10.1063/1.2906116",
language = "English (US)",
volume = "128",
journal = "Journal of Chemical Physics",
issn = "0021-9606",
publisher = "American Institute of Physics Publising LLC",
number = "18",

}

TY - JOUR

T1 - Effectively doubling the magnetic field in spin-1/2-spin-1, HSQC, HDQC, coupled HSQC, and coupled HDQC in solution NMR

AU - Shekar, S. Chandra

AU - Backer, Jonathan M.

AU - Girvin, Mark E.

PY - 2008

Y1 - 2008

N2 - Pulse sequences for spin- 1 2 -spin-1 pair heteronuclear single quantum correlation (HSQC), heteronuclear double quantum correlation (HDQC), and coupled-HSQC, and coupled-HDQC NMR spectroscopies are outlined, and experimental realization for a C13 - H2 pair is demonstrated in solution state. In both the coupled versions, conditions for generation of in-phase and antiphase multiplets in either dimension are arrived at. The patterns and the intensity ratios are explained. The double quantum (2Q) experiments confirm doubling of both the shift frequency and the splitting due to coupling (to spin 1 2) of the 2Q coherence emanating from spin 1. The frequency doubling is equivalent to the corresponding single quantum (1Q) coherence at double the magnetic field strength. The coupling doubling, however, is independent of the magnetic field strength and a signature feature of the 2Q coherence. The ramification of the relative relaxation rates of 1Q and 2Q coherences is discussed.

AB - Pulse sequences for spin- 1 2 -spin-1 pair heteronuclear single quantum correlation (HSQC), heteronuclear double quantum correlation (HDQC), and coupled-HSQC, and coupled-HDQC NMR spectroscopies are outlined, and experimental realization for a C13 - H2 pair is demonstrated in solution state. In both the coupled versions, conditions for generation of in-phase and antiphase multiplets in either dimension are arrived at. The patterns and the intensity ratios are explained. The double quantum (2Q) experiments confirm doubling of both the shift frequency and the splitting due to coupling (to spin 1 2) of the 2Q coherence emanating from spin 1. The frequency doubling is equivalent to the corresponding single quantum (1Q) coherence at double the magnetic field strength. The coupling doubling, however, is independent of the magnetic field strength and a signature feature of the 2Q coherence. The ramification of the relative relaxation rates of 1Q and 2Q coherences is discussed.

UR - http://www.scopus.com/inward/record.url?scp=43949097248&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=43949097248&partnerID=8YFLogxK

U2 - 10.1063/1.2906116

DO - 10.1063/1.2906116

M3 - Article

VL - 128

JO - Journal of Chemical Physics

JF - Journal of Chemical Physics

SN - 0021-9606

IS - 18

M1 - 184501

ER -