TY - JOUR
T1 - Dynamic T1-weighted magnetic resonance imaging of interstitial laser photocoagulation in the liver
T2 - Observations on in vivo temperature sensitivity
AU - Fried, Marvin P.
AU - Morrison, Paul R.
AU - Hushek, Stephen G.
AU - Kernahan, Gilberto A.
AU - Jolesz, Ferenc A.
PY - 1996
Y1 - 1996
N2 - Background and Objective: Magnetic resonance imaging's (MRI) potential to monitor interstitial laser photocoagulation (ILP) has been previously demonstrated and is further tested here with improved spatial and temporal resolution. Study Design/Materials and Methods: In vivo experiments employed fiber-delivered 1,064 nm light (3.0 W, 150 sec) in six rabbit livers monitored under T1-weighted FSE MRI as 1 image/10 sec and a 3 mm thick 8 cm FOV. Image signal intensities (SI) were compared with temperatures (T) at 7, 10, and 15 mm from the fiber. Results: Data showed 33°C < T < 60°C. SI did not vary inverse-linearly with T; changes in the tissue altered the MRI signal interfering with the SI changes due to temperature. Conclusion: MRI cannot map SI-derived temperatures over the entire treatment site. The role of MRI's temperature sensitivity must be coordinated with organ- and dose- specific tissue changes.
AB - Background and Objective: Magnetic resonance imaging's (MRI) potential to monitor interstitial laser photocoagulation (ILP) has been previously demonstrated and is further tested here with improved spatial and temporal resolution. Study Design/Materials and Methods: In vivo experiments employed fiber-delivered 1,064 nm light (3.0 W, 150 sec) in six rabbit livers monitored under T1-weighted FSE MRI as 1 image/10 sec and a 3 mm thick 8 cm FOV. Image signal intensities (SI) were compared with temperatures (T) at 7, 10, and 15 mm from the fiber. Results: Data showed 33°C < T < 60°C. SI did not vary inverse-linearly with T; changes in the tissue altered the MRI signal interfering with the SI changes due to temperature. Conclusion: MRI cannot map SI-derived temperatures over the entire treatment site. The role of MRI's temperature sensitivity must be coordinated with organ- and dose- specific tissue changes.
KW - Nd:YAG
KW - interstitial laser photocoagulation ILTT
KW - magnetic resonance imaging
KW - minimally invasive surgery
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U2 - 10.1002/(SICI)1096-9101(1996)18:4<410::AID-LSM11>3.0.CO;2-7
DO - 10.1002/(SICI)1096-9101(1996)18:4<410::AID-LSM11>3.0.CO;2-7
M3 - Article
C2 - 8732581
AN - SCOPUS:0029942580
SN - 0196-8092
VL - 18
SP - 410
EP - 419
JO - Lasers in Surgery and Medicine
JF - Lasers in Surgery and Medicine
IS - 4
ER -