Dynamic contrast-enhanced MRI for the analysis of blood-brain barrier leakage in traumatic brain injury

Qiang Shen, Timothy Q. Duong

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Blood-brain barrier (BBB) could be impaired following traumatic brain injury. Here we describe a modified technique for noninvasive longitudinal assessment of the of BBB integrity based on dynamic contrast-enhanced magnetic resonance imaging technique to evaluate the longitudinal progression of BBB leakage following traumatic brain injury in rats.

Original languageEnglish (US)
Title of host publicationNeuromethods
PublisherHumana Press Inc.
Pages271-282
Number of pages12
DOIs
StatePublished - 2018
Externally publishedYes

Publication series

NameNeuromethods
Volume139
ISSN (Print)0893-2336
ISSN (Electronic)1940-6045

Keywords

  • Blood-brain barrier
  • Dynamic contrast enhanced
  • Magnetic resonance imaging
  • Rodents
  • Traumatic brain injury

ASJC Scopus subject areas

  • Psychiatry and Mental health
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Biochemistry, Genetics and Molecular Biology
  • General Neuroscience

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