Drug-induced injury in the gastrointestinal tract

Nicole C. Panarelli

doi:10.1053/j.semdp.2014.02.007

Drug-induced injury in the gastrointestinal tract

Nicole C. Panarelli

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.

Original language	English (US)
Pages (from-to)	165-175
Number of pages	11
Journal	Seminars in Diagnostic Pathology
Volume	31
Issue number	2
DOIs	https://doi.org/10.1053/j.semdp.2014.02.007
State	Published - Mar 2014
Externally published	Yes

Keywords

Colchicine
Kayexalate
Mycophenolate mofetil
Olmesartan
Paclitaxel
Tetracycline

ASJC Scopus subject areas

Pathology and Forensic Medicine

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10.1053/j.semdp.2014.02.007

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AB - Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.

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KW - Kayexalate

KW - Mycophenolate mofetil

KW - Olmesartan

KW - Paclitaxel

KW - Tetracycline

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Drug-induced injury in the gastrointestinal tract

Abstract

Keywords

ASJC Scopus subject areas

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