Drug-induced injury in the gastrointestinal tract

Research output: Contribution to journalArticle

16 Citations (Scopus)

Abstract

Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.

Original languageEnglish (US)
Pages (from-to)165-175
Number of pages11
JournalSeminars in Diagnostic Pathology
Volume31
Issue number2
DOIs
StatePublished - 2014
Externally publishedYes

Fingerprint

Gastrointestinal Tract
Wounds and Injuries
Pharmaceutical Preparations
Caustics
Mucosal Immunity
Mucous Membrane
Biopsy
Pathologists

Keywords

  • Colchicine
  • Kayexalate
  • Mycophenolate mofetil
  • Olmesartan
  • Paclitaxel
  • Tetracycline

ASJC Scopus subject areas

  • Pathology and Forensic Medicine

Cite this

Drug-induced injury in the gastrointestinal tract. / Panarelli, Nicole C.

In: Seminars in Diagnostic Pathology, Vol. 31, No. 2, 2014, p. 165-175.

Research output: Contribution to journalArticle

@article{b30a56d4146642b1926f980ca1f32d61,
title = "Drug-induced injury in the gastrointestinal tract",
abstract = "Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.",
keywords = "Colchicine, Kayexalate, Mycophenolate mofetil, Olmesartan, Paclitaxel, Tetracycline",
author = "Panarelli, {Nicole C.}",
year = "2014",
doi = "10.1053/j.semdp.2014.02.007",
language = "English (US)",
volume = "31",
pages = "165--175",
journal = "Seminars in Diagnostic Pathology",
issn = "0740-2570",
publisher = "W.B. Saunders Ltd",
number = "2",

}

TY - JOUR

T1 - Drug-induced injury in the gastrointestinal tract

AU - Panarelli, Nicole C.

PY - 2014

Y1 - 2014

N2 - Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.

AB - Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.

KW - Colchicine

KW - Kayexalate

KW - Mycophenolate mofetil

KW - Olmesartan

KW - Paclitaxel

KW - Tetracycline

UR - http://www.scopus.com/inward/record.url?scp=84899822954&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84899822954&partnerID=8YFLogxK

U2 - 10.1053/j.semdp.2014.02.007

DO - 10.1053/j.semdp.2014.02.007

M3 - Article

VL - 31

SP - 165

EP - 175

JO - Seminars in Diagnostic Pathology

JF - Seminars in Diagnostic Pathology

SN - 0740-2570

IS - 2

ER -