Abstract
Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 165-175 |
| Number of pages | 11 |
| Journal | Seminars in Diagnostic Pathology |
| Volume | 31 |
| Issue number | 2 |
| DOIs | |
| State | Published - 2014 |
| Externally published | Yes |
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Keywords
- Colchicine
- Kayexalate
- Mycophenolate mofetil
- Olmesartan
- Paclitaxel
- Tetracycline
ASJC Scopus subject areas
- Pathology and Forensic Medicine
Cite this
Drug-induced injury in the gastrointestinal tract. / Panarelli, Nicole C.
In: Seminars in Diagnostic Pathology, Vol. 31, No. 2, 2014, p. 165-175.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Drug-induced injury in the gastrointestinal tract
AU - Panarelli, Nicole C.
PY - 2014
Y1 - 2014
N2 - Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.
AB - Abnormalities of the gastrointestinal tract due to drug-induced injuries are common and often have important clinical consequences. Medications may cause damage by direct corrosive effects on mucosae or by alter processes, mucosal immunity, and local environmental conditions. The aim of this review is to guide practicing pathologists in the identification of drug-related injuries in gastrointestinal mucosal biopsies and resection specimens. Common causes of injury and their gross, endoscopic, and microscopic features are presented.
KW - Colchicine
KW - Kayexalate
KW - Mycophenolate mofetil
KW - Olmesartan
KW - Paclitaxel
KW - Tetracycline
UR - http://www.scopus.com/inward/record.url?scp=84899822954&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84899822954&partnerID=8YFLogxK
U2 - 10.1053/j.semdp.2014.02.007
DO - 10.1053/j.semdp.2014.02.007
M3 - Article
VL - 31
SP - 165
EP - 175
JO - Seminars in Diagnostic Pathology
JF - Seminars in Diagnostic Pathology
SN - 0740-2570
IS - 2
ER -