Distinct light microscopic changes in human immunodeficiency virus- associated nemaline myopathy

Daniel M. Feinberg, Alfred J. Spiro, Karen M. Weidenheim

Research output: Contribution to journalArticle

36 Scopus citations


The purpose of this study was to compare histologic characteristics of congenital nemaline myopathy (CNM), adult-onset nemaline myopathy (AONM), and human immunodeficiency virus-associated adult-onset nemaline myopathy (HAONM). There was no difference between the pathology of CNM and AONM; however, HAONM had distinctive pathologic features by light microscopy. The fibers in HAONM showed marked intrasarcoplasmic changes, including small vacuoles and granular degeneration.

Original languageEnglish (US)
Pages (from-to)529-531
Number of pages3
Issue number2
StatePublished - Feb 1998


ASJC Scopus subject areas

  • Clinical Neurology

Cite this