Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Missak Haigentz; Dana M. Hartl; Carl E. Silver; Johannes A. Langendijk; Primož Strojan; Vinidh Paleri; Remco De Bree; Jean Pascal MacHiels; Marc Hamoir; Alessandra Rinaldo; Daniela Paccagnella; Ashok R. Shaha; Robert P. Takes; Alfio Ferlito

doi:10.1016/j.oraloncology.2012.03.019

Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Missak Haigentz, Dana M. Hartl, Carl E. Silver, Johannes A. Langendijk, Primož Strojan, Vinidh Paleri, Remco De Bree, Jean Pascal MacHiels, Marc Hamoir, Alessandra Rinaldo, Daniela Paccagnella, Ashok R. Shaha, Robert P. Takes, Alfio Ferlito

Medicine

Research output: Contribution to journal › Review article › peer-review

42 Scopus citations

Abstract

Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases.

Original language	English (US)
Pages (from-to)	787-793
Number of pages	7
Journal	Oral Oncology
Volume	48
Issue number	9
DOIs	https://doi.org/10.1016/j.oraloncology.2012.03.019
State	Published - Sep 2012

Keywords

Chemotherapy
Distant metastases
Head and neck squamous cell carcinoma
Metastasectomy
Treatment

ASJC Scopus subject areas

Oral Surgery
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/j.oraloncology.2012.03.019

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Haigentz, M., Hartl, D. M., Silver, C. E., Langendijk, J. A., Strojan, P., Paleri, V., De Bree, R., MacHiels, J. P., Hamoir, M., Rinaldo, A., Paccagnella, D., Shaha, A. R., Takes, R. P., & Ferlito, A. (2012). Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment. Oral Oncology, 48(9), 787-793. https://doi.org/10.1016/j.oraloncology.2012.03.019

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abstract = "Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases.",

keywords = "Chemotherapy, Distant metastases, Head and neck squamous cell carcinoma, Metastasectomy, Treatment",

author = "Missak Haigentz and Hartl, {Dana M.} and Silver, {Carl E.} and Langendijk, {Johannes A.} and Primo{\v z} Strojan and Vinidh Paleri and {De Bree}, Remco and MacHiels, {Jean Pascal} and Marc Hamoir and Alessandra Rinaldo and Daniela Paccagnella and Shaha, {Ashok R.} and Takes, {Robert P.} and Alfio Ferlito",

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AU - Haigentz, Missak

AU - Hartl, Dana M.

AU - Silver, Carl E.

AU - Langendijk, Johannes A.

AU - Strojan, Primož

AU - Paleri, Vinidh

AU - De Bree, Remco

AU - MacHiels, Jean Pascal

AU - Hamoir, Marc

AU - Rinaldo, Alessandra

AU - Paccagnella, Daniela

AU - Shaha, Ashok R.

AU - Takes, Robert P.

AU - Ferlito, Alfio

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AB - Distant metastases from head and neck squamous cell carcinoma (HNSCC), though rare at initial presentation, remain an important manifestation of cancer recurrence and mortality. Although generally considered incurable with a dismal prognosis despite palliative therapy, highly selected patients with distant metastases may have a long term survival benefit from aggressive surgery or radiotherapy. Advances in systemic treatments also may improve patient survival. This article reviews the current state of management of HNSCC patients with distant metastases.

KW - Chemotherapy

KW - Distant metastases

KW - Head and neck squamous cell carcinoma

KW - Metastasectomy

KW - Treatment

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Distant metastases from head and neck squamous cell carcinoma. Part III. Treatment

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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