Disseminated langerhans cell histiocytosis presenting as cholestatic jaundice

Rohit Kapoor, Anthony Meneloas Loizides, Soumya Sachdeva, Premila Paul

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Langerhans cell histiocytosis (LCH) is a disorder associated with proliferation of Langerhans cells in various organs. LCH secondary to multisystem involvement can present in a variety of ways. Because of its infiltrative nature, LCH can involve the skin, lymph nodes, the lung or the liver. Jaundice in LCH is a manifestation of liver disease; biliary dilatation secondary to lithiasis or may be due to coexistent Niemann-Pick disease. However, a case of cholestasis has been very rarely described. Cholestasis may result from lymph nodes obstructing the porta hepatis. In this report, we describe a case of type II histiocytosis X with obstructive cholestasis and pulmonary involvement in the form of cysts without significant lymphadenopathy at the porta.

Original languageEnglish (US)
Pages (from-to)SD03-SD05
JournalJournal of Clinical and Diagnostic Research
Volume9
Issue number2
DOIs
StatePublished - 2015

Fingerprint

Langerhans Cell Histiocytosis
Obstructive Jaundice
Liver
Cholestasis
Skin
Lymph Nodes
Niemann-Pick Diseases
Lung
Lithiasis
Langerhans Cells
Jaundice
Cysts
Liver Diseases
Dilatation

Keywords

  • Cholestasis
  • Lymphadenopathy
  • Porta hepatis

ASJC Scopus subject areas

  • Medicine(all)
  • Clinical Biochemistry

Cite this

Disseminated langerhans cell histiocytosis presenting as cholestatic jaundice. / Kapoor, Rohit; Loizides, Anthony Meneloas; Sachdeva, Soumya; Paul, Premila.

In: Journal of Clinical and Diagnostic Research, Vol. 9, No. 2, 2015, p. SD03-SD05.

Research output: Contribution to journalArticle

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