Disseminated Herpes Simplex Infection in an Immunocompromised Pregnancy: Treatment with Intravenous Acyclovir

Cynthia Chazotte, H. Frank Andersen, Wayne R. Cohen

Research output: Contribution to journalArticle

18 Scopus citations


In this article, we report a case of third-trimester disseminated herpes simplex virus (HSV) infection in an immunocompromised gravida who was treated with parenteral acyclovir. Rapid resolution of lesions occurred, and the fetus was delivered at term without evident abnormalities. Of the four previous reports on this therapy, there has been one maternal death and survival of all neonates. Acyclovir should be considered in the treatment of disseminated HSV infection in pregnancy.

Original languageEnglish (US)
Pages (from-to)363-364
Number of pages2
JournalAmerican Journal of Perinatology
Issue number4
Publication statusPublished - Oct 1987


ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Obstetrics and Gynecology

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