Disseminated hemangiosarcoma in a juvenile rhesus macaque (Macaca mulatta)

Amanda P. Beck, Stanton B. Gray, Beth K. Chaffee

Research output: Contribution to journalArticle

Abstract

Hemangiosarcoma is a malignant tumor of vascular endothelial origin that is sporadically reported in rhesus macaques. This report describes the clinicopathologic features of a 1-y-old rhesus macaque with spontaneous disseminated hemangiosarcoma that originally presented as a focal cutaneous mass. Histopathologic examination of multiple tumor foci revealed regions in which the neoplastic cells formed diffuse sheets, as well as the well-defined vascular channels typically associated with hemangiosarcoma. Multiple endothelial cell immunomarkers were used to confirm the diagnosis in this rhesus macaque. The tumor exhibited staining properties consistent with those seen in domestic animals and humans. In addition, to our knowledge, this animal represents the youngest case of any form of spontaneous hemangiosarcoma reported in the rhesus macaque to date.

Original languageEnglish (US)
Pages (from-to)246-253
Number of pages8
JournalComparative Medicine
Volume66
Issue number3
StatePublished - Jun 1 2016

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hemangiosarcoma
Hemangiosarcoma
Macaca mulatta
Tumors
Animals
blood vessels
neoplasms
Blood Vessels
Endothelial cells
Neoplasms
Domestic Animals
young animals
domestic animals
endothelial cells
Endothelial Cells
Staining and Labeling
Skin

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)
  • veterinary(all)

Cite this

Disseminated hemangiosarcoma in a juvenile rhesus macaque (Macaca mulatta). / Beck, Amanda P.; Gray, Stanton B.; Chaffee, Beth K.

In: Comparative Medicine, Vol. 66, No. 3, 01.06.2016, p. 246-253.

Research output: Contribution to journalArticle

Beck, Amanda P. ; Gray, Stanton B. ; Chaffee, Beth K. / Disseminated hemangiosarcoma in a juvenile rhesus macaque (Macaca mulatta). In: Comparative Medicine. 2016 ; Vol. 66, No. 3. pp. 246-253.
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