Abstract
A 56-year-old woman presented with a four-month history of transient obscurations of vision that progressed to constant visual loss. She had a nodular, lumpy-bumpy, cauliflower-like asymmetric edema of the nerve head, which suggested direct optic nerve head invasion with foreign tissue. Imaging of her intracranial contents revealed a well circumscribed gadolinium enhancing mass in the middle fossa. Histopathology of material obtained at craniotomy revealed noncaseating granulomata consistent with sarcoidosis. Central nervous system sarcoid may present either as an infiltrative granulomatous process, or one of discrete tumor mass, masquerading as a neoplasm. Neurologic symptoms and signs often herald the presence of systemic disease. Our case illustrates that isolated sarcoid optic neuropathy may occur and be associated with neither intraocular inflammatory signs nor extensive disease elsewhere; indeed, it may be the first declaration of neurosarcoidosis.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 133-139 |
| Number of pages | 7 |
| Journal | Survey of Ophthalmology |
| Volume | 36 |
| Issue number | 2 |
| DOIs | |
| State | Published - 1991 |
| Externally published | Yes |
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Keywords
- disc edema
- neurosarcoidosis
- visual obscurations
ASJC Scopus subject areas
- Ophthalmology
Cite this
Disc edema, transient obscurations of vision, and a temporal fossa mass. / Katz, Barrett.
In: Survey of Ophthalmology, Vol. 36, No. 2, 1991, p. 133-139.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Disc edema, transient obscurations of vision, and a temporal fossa mass
AU - Katz, Barrett
PY - 1991
Y1 - 1991
N2 - A 56-year-old woman presented with a four-month history of transient obscurations of vision that progressed to constant visual loss. She had a nodular, lumpy-bumpy, cauliflower-like asymmetric edema of the nerve head, which suggested direct optic nerve head invasion with foreign tissue. Imaging of her intracranial contents revealed a well circumscribed gadolinium enhancing mass in the middle fossa. Histopathology of material obtained at craniotomy revealed noncaseating granulomata consistent with sarcoidosis. Central nervous system sarcoid may present either as an infiltrative granulomatous process, or one of discrete tumor mass, masquerading as a neoplasm. Neurologic symptoms and signs often herald the presence of systemic disease. Our case illustrates that isolated sarcoid optic neuropathy may occur and be associated with neither intraocular inflammatory signs nor extensive disease elsewhere; indeed, it may be the first declaration of neurosarcoidosis.
AB - A 56-year-old woman presented with a four-month history of transient obscurations of vision that progressed to constant visual loss. She had a nodular, lumpy-bumpy, cauliflower-like asymmetric edema of the nerve head, which suggested direct optic nerve head invasion with foreign tissue. Imaging of her intracranial contents revealed a well circumscribed gadolinium enhancing mass in the middle fossa. Histopathology of material obtained at craniotomy revealed noncaseating granulomata consistent with sarcoidosis. Central nervous system sarcoid may present either as an infiltrative granulomatous process, or one of discrete tumor mass, masquerading as a neoplasm. Neurologic symptoms and signs often herald the presence of systemic disease. Our case illustrates that isolated sarcoid optic neuropathy may occur and be associated with neither intraocular inflammatory signs nor extensive disease elsewhere; indeed, it may be the first declaration of neurosarcoidosis.
KW - disc edema
KW - neurosarcoidosis
KW - visual obscurations
UR - http://www.scopus.com/inward/record.url?scp=0026093992&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026093992&partnerID=8YFLogxK
U2 - 10.1016/0039-6257(91)90126-Z
DO - 10.1016/0039-6257(91)90126-Z
M3 - Article
C2 - 1957245
AN - SCOPUS:0026093992
VL - 36
SP - 133
EP - 139
JO - Survey of Ophthalmology
JF - Survey of Ophthalmology
SN - 0039-6257
IS - 2
ER -