Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome

Farhad Sahebjam, Cristina H. Hajdu, Esther Nortey, Samuel H. Sigal

Research output: Contribution to journalArticle

1 Citation (Scopus)

Abstract

Autoimmune phenomena are common in patients with chronic hepatitis C. Management of chronic hepatitis C/autoimmune hepatitis syndrome has until recently been problematic due to the adverse effects of interferon on autoimmune processes and immunosuppression on viral replication. In this report we describe 3 patients with chronic hepatitis C/autoimmune hepatitis overlap syndrome who responded rapidly to direct acting antiviral therapy. The resolution of the autoimmune process supports a direct viral role in its pathophysiology.

Original languageEnglish (US)
Pages (from-to)632-636
Number of pages5
JournalWorld Journal of Hepatology
Volume8
Issue number14
DOIs
StatePublished - May 18 2016

Fingerprint

Autoimmune Hepatitis
Chronic Hepatitis C
Antiviral Agents
Immunosuppression
Interferons
Therapeutics

Keywords

  • Autoimmune hepatitis
  • Direct acting antiviral therapy
  • Hepatitis C
  • Overlap syndrome

ASJC Scopus subject areas

  • Hepatology

Cite this

Direct acting antiviral therapy is curative for chronic hepatitis C/autoimmune hepatitis overlap syndrome. / Sahebjam, Farhad; Hajdu, Cristina H.; Nortey, Esther; Sigal, Samuel H.

In: World Journal of Hepatology, Vol. 8, No. 14, 18.05.2016, p. 632-636.

Research output: Contribution to journalArticle

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