Differentiation of intercalated cells in the kidney

Qais Al-Awqati, Xaio Bo Gao

Research output: Contribution to journalReview article

27 Scopus citations


The intercalated cell of collecting ducts of the kidney is of two forms, the β form secretes acid, whereas the α form secretes HCO3. Here, we review recent work that shows that the α form is derived from the β form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.

Original languageEnglish (US)
Pages (from-to)266-272
Number of pages7
Issue number4
Publication statusPublished - Aug 1 2011
Externally publishedYes


ASJC Scopus subject areas

  • Physiology

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