Differentiation of intercalated cells in the kidney

Qais Al-Awqati; Xaio Bo Gao

doi:10.1152/physiol.00008.2011

Differentiation of intercalated cells in the kidney

Qais Al-Awqati, Xaio Bo Gao

Research output: Contribution to journal › Review article › peer-review

37 Scopus citations

Abstract

The intercalated cell of collecting ducts of the kidney is of two forms, the β form secretes acid, whereas the α form secretes HCO3. Here, we review recent work that shows that the α form is derived from the β form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.

Original language	English (US)
Pages (from-to)	266-272
Number of pages	7
Journal	Physiology
Volume	26
Issue number	4
DOIs	https://doi.org/10.1152/physiol.00008.2011
State	Published - Aug 2011
Externally published	Yes

ASJC Scopus subject areas

Physiology

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10.1152/physiol.00008.2011

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title = "Differentiation of intercalated cells in the kidney",

abstract = "The intercalated cell of collecting ducts of the kidney is of two forms, the β form secretes acid, whereas the α form secretes HCO3. Here, we review recent work that shows that the α form is derived from the β form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.",

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AB - The intercalated cell of collecting ducts of the kidney is of two forms, the β form secretes acid, whereas the α form secretes HCO3. Here, we review recent work that shows that the α form is derived from the β form and that the pathway is mediated by an extracellular matrix protein called hensin/DMBT1.

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Differentiation of intercalated cells in the kidney

Abstract

ASJC Scopus subject areas

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