Diazepam in the management of heroin withdrawal in adolescents: Preliminary report

Iris F. Litt, Anita S. Colli, Michael I. Cohen

Research output: Contribution to journalArticle

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Abstract

In a group of mice experimentally addicted to morphine, diazepam eliminated the major manifestation of withdrawal. Diazepam was similarly effective in reducing the duration and severity of withdrawal symptoms in a large group of adolescent heroin addicts. The ideal agent for opiate detoxification is one which is nontoxic, nonaddictive, inexpensive, easily administered, and above all, effective in eliminating the potentially life-threatening consequences of withdrawal. On the basis of the animal experiment and clinical trial in adolescent heroin addicts reported herein, diazepam appears to fulfill these criteria.

Original languageEnglish (US)
Pages (from-to)692-696
Number of pages5
JournalThe Journal of Pediatrics
Volume78
Issue number4
DOIs
StatePublished - Apr 1971

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ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

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