Descemet Stripping Endothelial Keratoplasty in Eyes With Previous Glaucoma Surgery

Joann J. Kang, David C. Ritterband, Kevin Lai, Jeffrey M. Liebmann, John A. Seedor

Research output: Contribution to journalArticle

9 Citations (Scopus)

Abstract

PURPOSE:: To evaluate visual outcomes and complications after Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with previous glaucoma surgery. METHODS:: A retrospective chart review was conducted of 129 procedures in 102 eyes of 96 patients who underwent DSAEK and previous glaucoma surgery at New York Eye and Ear Infirmary of Mt Sinai. The mean length of follow-up was 29.1 ± 25.5 months. Patients with postoperative follow-up duration of less than 3 months were excluded from analysis. Intraoperative and postoperative complications, postoperative course, and visual outcomes were analyzed. RESULTS:: Graft dislocation occurred in 46 eyes (35.7%) and 38 eyes required repeat injection of air in the anterior chamber. Primary graft failure occurred in 3 eyes (2.3%), early graft failure in 20 eyes (15.5%), and secondary graft failure developed in 29 eyes (22.5%). There was a statistically significant increase in secondary graft failure in patients with previous aqueous shunt implantation compared with eyes with previous trabeculectomy (P = 0.03). Escalation of glaucoma therapy was needed medically in 25 eyes (24.5%), and 8 eyes (7.8%) required additional surgical intervention. CONCLUSIONS:: There is a significant incidence of graft dislocation and graft failure after DSAEK in eyes with previous glaucoma surgery. In particular, aqueous shunt surgery compared with trabeculectomy may decrease long-term graft survival, and close follow-up is warranted.

Original languageEnglish (US)
JournalCornea
DOIs
StateAccepted/In press - Oct 14 2016

Fingerprint

Descemet Stripping Endothelial Keratoplasty
Glaucoma
Transplants
Glaucoma Drainage Implants
Trabeculectomy
Intraoperative Complications
Anterior Chamber
Graft Survival
Ear

ASJC Scopus subject areas

  • Ophthalmology

Cite this

Descemet Stripping Endothelial Keratoplasty in Eyes With Previous Glaucoma Surgery. / Kang, Joann J.; Ritterband, David C.; Lai, Kevin; Liebmann, Jeffrey M.; Seedor, John A.

In: Cornea, 14.10.2016.

Research output: Contribution to journalArticle

Kang, Joann J. ; Ritterband, David C. ; Lai, Kevin ; Liebmann, Jeffrey M. ; Seedor, John A. / Descemet Stripping Endothelial Keratoplasty in Eyes With Previous Glaucoma Surgery. In: Cornea. 2016.
@article{9fe4bf8819594a70bf2cb8cc212d810c,
title = "Descemet Stripping Endothelial Keratoplasty in Eyes With Previous Glaucoma Surgery",
abstract = "PURPOSE:: To evaluate visual outcomes and complications after Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with previous glaucoma surgery. METHODS:: A retrospective chart review was conducted of 129 procedures in 102 eyes of 96 patients who underwent DSAEK and previous glaucoma surgery at New York Eye and Ear Infirmary of Mt Sinai. The mean length of follow-up was 29.1 ± 25.5 months. Patients with postoperative follow-up duration of less than 3 months were excluded from analysis. Intraoperative and postoperative complications, postoperative course, and visual outcomes were analyzed. RESULTS:: Graft dislocation occurred in 46 eyes (35.7{\%}) and 38 eyes required repeat injection of air in the anterior chamber. Primary graft failure occurred in 3 eyes (2.3{\%}), early graft failure in 20 eyes (15.5{\%}), and secondary graft failure developed in 29 eyes (22.5{\%}). There was a statistically significant increase in secondary graft failure in patients with previous aqueous shunt implantation compared with eyes with previous trabeculectomy (P = 0.03). Escalation of glaucoma therapy was needed medically in 25 eyes (24.5{\%}), and 8 eyes (7.8{\%}) required additional surgical intervention. CONCLUSIONS:: There is a significant incidence of graft dislocation and graft failure after DSAEK in eyes with previous glaucoma surgery. In particular, aqueous shunt surgery compared with trabeculectomy may decrease long-term graft survival, and close follow-up is warranted.",
author = "Kang, {Joann J.} and Ritterband, {David C.} and Kevin Lai and Liebmann, {Jeffrey M.} and Seedor, {John A.}",
year = "2016",
month = "10",
day = "14",
doi = "10.1097/ICO.0000000000001058",
language = "English (US)",
journal = "Cornea",
issn = "0277-3740",
publisher = "Lippincott Williams and Wilkins",

}

TY - JOUR

T1 - Descemet Stripping Endothelial Keratoplasty in Eyes With Previous Glaucoma Surgery

AU - Kang, Joann J.

AU - Ritterband, David C.

AU - Lai, Kevin

AU - Liebmann, Jeffrey M.

AU - Seedor, John A.

PY - 2016/10/14

Y1 - 2016/10/14

N2 - PURPOSE:: To evaluate visual outcomes and complications after Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with previous glaucoma surgery. METHODS:: A retrospective chart review was conducted of 129 procedures in 102 eyes of 96 patients who underwent DSAEK and previous glaucoma surgery at New York Eye and Ear Infirmary of Mt Sinai. The mean length of follow-up was 29.1 ± 25.5 months. Patients with postoperative follow-up duration of less than 3 months were excluded from analysis. Intraoperative and postoperative complications, postoperative course, and visual outcomes were analyzed. RESULTS:: Graft dislocation occurred in 46 eyes (35.7%) and 38 eyes required repeat injection of air in the anterior chamber. Primary graft failure occurred in 3 eyes (2.3%), early graft failure in 20 eyes (15.5%), and secondary graft failure developed in 29 eyes (22.5%). There was a statistically significant increase in secondary graft failure in patients with previous aqueous shunt implantation compared with eyes with previous trabeculectomy (P = 0.03). Escalation of glaucoma therapy was needed medically in 25 eyes (24.5%), and 8 eyes (7.8%) required additional surgical intervention. CONCLUSIONS:: There is a significant incidence of graft dislocation and graft failure after DSAEK in eyes with previous glaucoma surgery. In particular, aqueous shunt surgery compared with trabeculectomy may decrease long-term graft survival, and close follow-up is warranted.

AB - PURPOSE:: To evaluate visual outcomes and complications after Descemet stripping automated endothelial keratoplasty (DSAEK) in patients with previous glaucoma surgery. METHODS:: A retrospective chart review was conducted of 129 procedures in 102 eyes of 96 patients who underwent DSAEK and previous glaucoma surgery at New York Eye and Ear Infirmary of Mt Sinai. The mean length of follow-up was 29.1 ± 25.5 months. Patients with postoperative follow-up duration of less than 3 months were excluded from analysis. Intraoperative and postoperative complications, postoperative course, and visual outcomes were analyzed. RESULTS:: Graft dislocation occurred in 46 eyes (35.7%) and 38 eyes required repeat injection of air in the anterior chamber. Primary graft failure occurred in 3 eyes (2.3%), early graft failure in 20 eyes (15.5%), and secondary graft failure developed in 29 eyes (22.5%). There was a statistically significant increase in secondary graft failure in patients with previous aqueous shunt implantation compared with eyes with previous trabeculectomy (P = 0.03). Escalation of glaucoma therapy was needed medically in 25 eyes (24.5%), and 8 eyes (7.8%) required additional surgical intervention. CONCLUSIONS:: There is a significant incidence of graft dislocation and graft failure after DSAEK in eyes with previous glaucoma surgery. In particular, aqueous shunt surgery compared with trabeculectomy may decrease long-term graft survival, and close follow-up is warranted.

UR - http://www.scopus.com/inward/record.url?scp=84991489714&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84991489714&partnerID=8YFLogxK

U2 - 10.1097/ICO.0000000000001058

DO - 10.1097/ICO.0000000000001058

M3 - Article

JO - Cornea

JF - Cornea

SN - 0277-3740

ER -