Demonstration of Nitrogen Coordination in Metal-Bleomycin Complexes by Electron Spin-Echo Envelope Spectroscopy

R. M. Burger, A. D. Adler, S. B. Horwitz, W. B. Mims, J. Peisach

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

We have studied the Cu(II), Co(II), and Fe(III) complexes of the antineoplastic drug bleomycin by using electron spin-echo envelope spectroscopy. For all three complexes, nitrogen coordination of the metal ion is demonstrated For the Cu(II)- and Co(II)-drug complexes, we have been able to identify imidazole as a metal ligand.

Original languageEnglish (US)
Pages (from-to)1701-1704
Number of pages4
JournalBiochemistry
Volume20
Issue number6
DOIs
StatePublished - Mar 1981

ASJC Scopus subject areas

  • Biochemistry

Fingerprint Dive into the research topics of 'Demonstration of Nitrogen Coordination in Metal-Bleomycin Complexes by Electron Spin-Echo Envelope Spectroscopy'. Together they form a unique fingerprint.

  • Cite this