Deep sedation with propofol for children undergoing ambulatory magnetic resonance imaging of the brain: Experience from a pediatric intensive care unit

Rashed A. Hasan, Jay R. Shayevitz, Vipul Patel

Research output: Contribution to journalArticle

52 Citations (Scopus)

Abstract

Objectives: Use of intravenous propofol sedation to facilitate completion of magnetic resonance imaging of the brain in children. Design: Retrospective, cross-sectional. Setting: A university-affiliated pediatric intensive care unit. Patients: A total of 115 children who received intravenous propofol to complete magnetic resonance imaging of the brain January 1 through December 31, 2001. Interventions: Intravenous propofol infusion. Measurements and Main Results: The mean age was 4.2±3.1 yrs, and there were 63 boys and 52 girls. Sixty-nine percent of patients belonged to ASA physical status class I, and 31% belonged to ASA class II. All studies were completed with satisfactory image quality. The total dose of propofol used to complete a magnetic resonance image of the brain was 4.3±1.7 mg/kg body weight. The mean duration of sedation induction was 4.5 ±3.5 mins. The mean time to recovery (from the end of the procedure) was 20±15 mins. The duration of the procedure averaged 39±20 mins, and the time to discharge from the hospital was 50±21 mins from the end of the procedure. No episodes of hypoxia, apnea, or a need for artificial airway were noted. Systolic blood pressure decreased 10%±13%, but none of the patients met the criteria for hypotension. A telephone call the next day to the family did not reveal any delayed complications. Conclusions: Propofol can safely facilitate ambulatory magnetic resonance imaging of the brain in children, and it is associated with brief induction, recovery, and discharge times from the hospital. A drop in blood pressure, although mild and transient, does occur. Therefore, appropriate monitoring and preparedness for cardiorespiratory support are essential. (Pediatr Crit Care Med 2003; 4:454 -458).

Original languageEnglish (US)
Pages (from-to)454-458
Number of pages5
JournalPediatric Critical Care Medicine
Volume4
Issue number4
DOIs
StatePublished - 2003
Externally publishedYes

Fingerprint

Deep Sedation
Pediatric Intensive Care Units
Propofol
Magnetic Resonance Imaging
Brain
Blood Pressure
Apnea
Telephone
Intravenous Infusions
Hypotension
Magnetic Resonance Spectroscopy
Body Weight

Keywords

  • Magnetic resonance imaging
  • Mmmobilization
  • Motion artifacts
  • Propofol
  • Sedation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Critical Care and Intensive Care Medicine

Cite this

Deep sedation with propofol for children undergoing ambulatory magnetic resonance imaging of the brain : Experience from a pediatric intensive care unit. / Hasan, Rashed A.; Shayevitz, Jay R.; Patel, Vipul.

In: Pediatric Critical Care Medicine, Vol. 4, No. 4, 2003, p. 454-458.

Research output: Contribution to journalArticle

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abstract = "Objectives: Use of intravenous propofol sedation to facilitate completion of magnetic resonance imaging of the brain in children. Design: Retrospective, cross-sectional. Setting: A university-affiliated pediatric intensive care unit. Patients: A total of 115 children who received intravenous propofol to complete magnetic resonance imaging of the brain January 1 through December 31, 2001. Interventions: Intravenous propofol infusion. Measurements and Main Results: The mean age was 4.2±3.1 yrs, and there were 63 boys and 52 girls. Sixty-nine percent of patients belonged to ASA physical status class I, and 31{\%} belonged to ASA class II. All studies were completed with satisfactory image quality. The total dose of propofol used to complete a magnetic resonance image of the brain was 4.3±1.7 mg/kg body weight. The mean duration of sedation induction was 4.5 ±3.5 mins. The mean time to recovery (from the end of the procedure) was 20±15 mins. The duration of the procedure averaged 39±20 mins, and the time to discharge from the hospital was 50±21 mins from the end of the procedure. No episodes of hypoxia, apnea, or a need for artificial airway were noted. Systolic blood pressure decreased 10{\%}±13{\%}, but none of the patients met the criteria for hypotension. A telephone call the next day to the family did not reveal any delayed complications. Conclusions: Propofol can safely facilitate ambulatory magnetic resonance imaging of the brain in children, and it is associated with brief induction, recovery, and discharge times from the hospital. A drop in blood pressure, although mild and transient, does occur. Therefore, appropriate monitoring and preparedness for cardiorespiratory support are essential. (Pediatr Crit Care Med 2003; 4:454 -458).",
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AB - Objectives: Use of intravenous propofol sedation to facilitate completion of magnetic resonance imaging of the brain in children. Design: Retrospective, cross-sectional. Setting: A university-affiliated pediatric intensive care unit. Patients: A total of 115 children who received intravenous propofol to complete magnetic resonance imaging of the brain January 1 through December 31, 2001. Interventions: Intravenous propofol infusion. Measurements and Main Results: The mean age was 4.2±3.1 yrs, and there were 63 boys and 52 girls. Sixty-nine percent of patients belonged to ASA physical status class I, and 31% belonged to ASA class II. All studies were completed with satisfactory image quality. The total dose of propofol used to complete a magnetic resonance image of the brain was 4.3±1.7 mg/kg body weight. The mean duration of sedation induction was 4.5 ±3.5 mins. The mean time to recovery (from the end of the procedure) was 20±15 mins. The duration of the procedure averaged 39±20 mins, and the time to discharge from the hospital was 50±21 mins from the end of the procedure. No episodes of hypoxia, apnea, or a need for artificial airway were noted. Systolic blood pressure decreased 10%±13%, but none of the patients met the criteria for hypotension. A telephone call the next day to the family did not reveal any delayed complications. Conclusions: Propofol can safely facilitate ambulatory magnetic resonance imaging of the brain in children, and it is associated with brief induction, recovery, and discharge times from the hospital. A drop in blood pressure, although mild and transient, does occur. Therefore, appropriate monitoring and preparedness for cardiorespiratory support are essential. (Pediatr Crit Care Med 2003; 4:454 -458).

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