D-lactic acidosis mediated neuronal encephalopathy in acute lymphoblastic leukemia patient: An under diagnosis

Damodara Rao Mendu, Martin Fleisher, Samuel I. McCash, Melissa S. Pessin, Lakshmi V. Ramanathan

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: D-lactic acidosis, also referred as D-lactate encephalopathy, has been reported in patients with short bowl syndrome (SBS). Case report: The neurologic symptoms include altered mental status, slurred speech, and ataxia. Onset of neurological symptoms is accompanied by metabolic acidosis and high anion gap. We present here a case of D-lactic acidosis in a patient with acute lymphoblastic leukemia (ALL) who developed severe neurological symptoms and metabolic acidosis due to vancomycin-resistant enterococci (VRE) infection, and elevated D-lactic acid.

Original languageEnglish (US)
Pages (from-to)90-91
Number of pages2
JournalClinica Chimica Acta
Volume441
DOIs
StatePublished - Feb 4 2015
Externally publishedYes

Fingerprint

Lactic Acidosis
Brain Diseases
Acidosis
Precursor Cell Lymphoblastic Leukemia-Lymphoma
Lactic Acid
Acid-Base Equilibrium
Ataxia
Vancomycin
Neurologic Manifestations
Infection
Milk
Vancomycin-Resistant Enterococci
SHORT syndrome

Keywords

  • D-lactic acid
  • Hematological malignancy
  • Neuropathy

ASJC Scopus subject areas

  • Biochemistry
  • Clinical Biochemistry
  • Biochemistry, medical

Cite this

D-lactic acidosis mediated neuronal encephalopathy in acute lymphoblastic leukemia patient : An under diagnosis. / Mendu, Damodara Rao; Fleisher, Martin; McCash, Samuel I.; Pessin, Melissa S.; Ramanathan, Lakshmi V.

In: Clinica Chimica Acta, Vol. 441, 04.02.2015, p. 90-91.

Research output: Contribution to journalArticle

Mendu, Damodara Rao ; Fleisher, Martin ; McCash, Samuel I. ; Pessin, Melissa S. ; Ramanathan, Lakshmi V. / D-lactic acidosis mediated neuronal encephalopathy in acute lymphoblastic leukemia patient : An under diagnosis. In: Clinica Chimica Acta. 2015 ; Vol. 441. pp. 90-91.
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