Corneal sensitivity in nephropathic cystinosis

Barrett Katz, Ronald B. Melles, Jerry A. Schneider

Research output: Contribution to journalArticle

7 Scopus citations

Abstract

We measured corneal sensitivity in 14 patients with infantile nephropathic cystinosis and in 13 age-matched controls. All patients with cystinosis had the pathognomonic anterior segment findings of crystal deposition within conjunctiva and cornea. Transcutaneous stimulation of the supraorbital nerve and surface electromyographic recording of the orbicularis oculi muscle performed on four patients showed a normal afferent limb to the blink reflex. The corneal sensitivity in patients with cystinosis was 3.18 g/mm2; in the control subjects it was 0.43 g/mm2. This difference was statistically significant (P < .001).

Original languageEnglish (US)
Pages (from-to)413-416
Number of pages4
JournalAmerican journal of ophthalmology
Volume104
Issue number4
DOIs
StatePublished - Oct 15 1987

ASJC Scopus subject areas

  • Ophthalmology

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