Corneal sensitivity in nephropathic cystinosis

Barrett Katz; Ronald B. Melles; Jerry A. Schneider

doi:10.1016/0002-9394(87)90233-9

Corneal sensitivity in nephropathic cystinosis

Barrett Katz, Ronald B. Melles, Jerry A. Schneider

Research output: Contribution to journal › Article › peer-review

9 Scopus citations

Abstract

We measured corneal sensitivity in 14 patients with infantile nephropathic cystinosis and in 13 age-matched controls. All patients with cystinosis had the pathognomonic anterior segment findings of crystal deposition within conjunctiva and cornea. Transcutaneous stimulation of the supraorbital nerve and surface electromyographic recording of the orbicularis oculi muscle performed on four patients showed a normal afferent limb to the blink reflex. The corneal sensitivity in patients with cystinosis was 3.18 g/mm²; in the control subjects it was 0.43 g/mm². This difference was statistically significant (P < .001).

Original language	English (US)
Pages (from-to)	413-416
Number of pages	4
Journal	American journal of ophthalmology
Volume	104
Issue number	4
DOIs	https://doi.org/10.1016/0002-9394(87)90233-9
State	Published - Oct 15 1987
Externally published	Yes

ASJC Scopus subject areas

Ophthalmology

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10.1016/0002-9394(87)90233-9

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abstract = "We measured corneal sensitivity in 14 patients with infantile nephropathic cystinosis and in 13 age-matched controls. All patients with cystinosis had the pathognomonic anterior segment findings of crystal deposition within conjunctiva and cornea. Transcutaneous stimulation of the supraorbital nerve and surface electromyographic recording of the orbicularis oculi muscle performed on four patients showed a normal afferent limb to the blink reflex. The corneal sensitivity in patients with cystinosis was 3.18 g/mm2; in the control subjects it was 0.43 g/mm2. This difference was statistically significant (P < .001).",

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AU - Schneider, Jerry A.

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N2 - We measured corneal sensitivity in 14 patients with infantile nephropathic cystinosis and in 13 age-matched controls. All patients with cystinosis had the pathognomonic anterior segment findings of crystal deposition within conjunctiva and cornea. Transcutaneous stimulation of the supraorbital nerve and surface electromyographic recording of the orbicularis oculi muscle performed on four patients showed a normal afferent limb to the blink reflex. The corneal sensitivity in patients with cystinosis was 3.18 g/mm2; in the control subjects it was 0.43 g/mm2. This difference was statistically significant (P < .001).

AB - We measured corneal sensitivity in 14 patients with infantile nephropathic cystinosis and in 13 age-matched controls. All patients with cystinosis had the pathognomonic anterior segment findings of crystal deposition within conjunctiva and cornea. Transcutaneous stimulation of the supraorbital nerve and surface electromyographic recording of the orbicularis oculi muscle performed on four patients showed a normal afferent limb to the blink reflex. The corneal sensitivity in patients with cystinosis was 3.18 g/mm2; in the control subjects it was 0.43 g/mm2. This difference was statistically significant (P < .001).

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Corneal sensitivity in nephropathic cystinosis

Abstract

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