Coordinating cell proliferation and differentiation

Liang Zhu; Arthur I. Skoultchi

doi:10.1016/S0959-437X(00)00162-3

Coordinating cell proliferation and differentiation

Liang Zhu, Arthur I. Skoultchi

Research output: Contribution to journal › Review article › peer-review

180 Scopus citations

Abstract

Cell proliferation and differentiation are highly coordinated processes during development. Recent studies have revealed that this coordination may result from dual functions residing in the central regulators of proliferation, allowing them to also regulate differentiation. Studies have also shown that some terminally differentiated cells can be made to divide beyond their normal capacity.

Original language	English (US)
Pages (from-to)	91-97
Number of pages	7
Journal	Current Opinion in Genetics and Development
Volume	11
Issue number	1
DOIs	https://doi.org/10.1016/S0959-437X(00)00162-3
State	Published - 2001

ASJC Scopus subject areas

Genetics
Developmental Biology

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10.1016/S0959-437X(00)00162-3

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title = "Coordinating cell proliferation and differentiation",

abstract = "Cell proliferation and differentiation are highly coordinated processes during development. Recent studies have revealed that this coordination may result from dual functions residing in the central regulators of proliferation, allowing them to also regulate differentiation. Studies have also shown that some terminally differentiated cells can be made to divide beyond their normal capacity.",

author = "Liang Zhu and Skoultchi, {Arthur I.}",

note = "Funding Information: The authors{\textquoteright} laboratories are supported by National Institutes of Health grants (L Zhu and AI Skoultchi), and grants from US Army and the American Cancer Society (L Zhu). L Zhu is a Leukemia & Lymphoma Society Scholar. ",

year = "2001",

doi = "10.1016/S0959-437X(00)00162-3",

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T1 - Coordinating cell proliferation and differentiation

AU - Zhu, Liang

AU - Skoultchi, Arthur I.

N1 - Funding Information: The authors’ laboratories are supported by National Institutes of Health grants (L Zhu and AI Skoultchi), and grants from US Army and the American Cancer Society (L Zhu). L Zhu is a Leukemia & Lymphoma Society Scholar.

PY - 2001

Y1 - 2001

N2 - Cell proliferation and differentiation are highly coordinated processes during development. Recent studies have revealed that this coordination may result from dual functions residing in the central regulators of proliferation, allowing them to also regulate differentiation. Studies have also shown that some terminally differentiated cells can be made to divide beyond their normal capacity.

AB - Cell proliferation and differentiation are highly coordinated processes during development. Recent studies have revealed that this coordination may result from dual functions residing in the central regulators of proliferation, allowing them to also regulate differentiation. Studies have also shown that some terminally differentiated cells can be made to divide beyond their normal capacity.

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DO - 10.1016/S0959-437X(00)00162-3

M3 - Review article

C2 - 11163157

AN - SCOPUS:0035253718

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EP - 97

JO - Current Opinion in Genetics and Development

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Coordinating cell proliferation and differentiation

Abstract

ASJC Scopus subject areas

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