Convulsive status epilepticus in children

V. Gross-Tsur, Shlomo Shinnar

Research output: Contribution to journalArticle

63 Citations (Scopus)

Abstract

Status epilepticus (SE) occurs most commonly in infancy and childhood. Children with prior neurological abnormalities are most susceptible. More than 90% of cases are convulsive and the majority are generalized. SE may occur in the setting of an acute illness, in patients with established epilepsy or as a first unprovoked seizure. The etiology can be classified as idiopathic, remote symptomatic, febrile, acute symptomatic, or associated with a progressive encephalopathy. The morbidity and mortality of status have dramatically declined in recent years. Overall mortality in recent pediatric series was 3-10%, with almost all fatalities associated with acute central nervous system insults or progressive neurologic disorders. Neurological sequelae in children with idiopathic or febrile status are rare. Neurologically normal children with SE as their first unprovoked seizure have the same risk of experiencing subsequent seizures of any type as children who present with a brief first seizure. The risk of recurrent episodes of convulsive SE approaches 50% in neurologically abnormal children but is very low in neurologically normal children. The favorable outcome of SE in children may be related to advances in therapy and to the resistance of the immature brain to damage from seizures.

Original languageEnglish (US)
JournalEpilepsia
Volume34
Issue numberSUPPL. 1
StatePublished - 1993

Fingerprint

Status Epilepticus
Seizures
Fever
Mortality
Brain Diseases
Nervous System Diseases
Epilepsy
Central Nervous System
Pediatrics
Morbidity
Brain

Keywords

  • Adolescents
  • Children
  • Electroencephalography
  • Emergency treatment
  • Epidemiology
  • Epilepsy
  • Febrile seizures
  • Focal epilepsy
  • Generalized epilepsy
  • Morbidity
  • Mortality
  • Status epilepticus

ASJC Scopus subject areas

  • Clinical Neurology
  • Neuroscience(all)

Cite this

Convulsive status epilepticus in children. / Gross-Tsur, V.; Shinnar, Shlomo.

In: Epilepsia, Vol. 34, No. SUPPL. 1, 1993.

Research output: Contribution to journalArticle

Gross-Tsur, V & Shinnar, S 1993, 'Convulsive status epilepticus in children', Epilepsia, vol. 34, no. SUPPL. 1.
Gross-Tsur, V. ; Shinnar, Shlomo. / Convulsive status epilepticus in children. In: Epilepsia. 1993 ; Vol. 34, No. SUPPL. 1.
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