Conformational freedom in tight binding enzymatic transition-state analogues

Physics & Astronomy

• cholera 90%
• affinity 72%
• analogs 63%
• proteins 31%
• inhibitors 30%
• antibiotics 18%
• Escherichia 15%
• bacteria 14%
• enzymes 14%
• flexibility 11%
• interactions 10%
• crystal structure 10%
• simulation 10%
• electrostatics 9%
• molecular dynamics 9%
• atoms 6%

Engineering & Materials Science

• Escherichia coli 100%
• Proteins 30%
• Coulomb interactions 17%
• Antibiotics 16%
• Crystal structure 14%
• Enzymes 12%
• Molecular dynamics 12%
• Bacteria 12%
• Atoms 11%
• Computer simulation 6%

Chemical Compounds

• Transition State 64%
• Simulation 33%
• Protein 21%
• Flexibility 20%
• Molecular Dynamics 19%
• Antimicrobial Agent 18%
• Resistance 16%
• Pressure 15%
• Crystal Structure 13%