Computed tomography and neurological soft signs in obsessive-compulsive disorder

Dan J. Stein; Eric Hollander; Chan Stephen; Concetta M. DeCaria; Sadek Hilal; Michael R. Liebowitz; Donald F. Klein

doi:10.1016/0925-4927(93)90026-E

Computed tomography and neurological soft signs in obsessive-compulsive disorder

Dan J. Stein, Eric Hollander, Chan Stephen, Concetta M. DeCaria, Sadek Hilal, Michael R. Liebowitz, Donald F. Klein

Research output: Contribution to journal › Article › peer-review

49 Scopus citations

Abstract

Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores and control subjects. Neuroanatomical structures were measured using quantitative volumetric analysis. OCD patients with high soft sign scores had significantly increased ventricular volumes compared with OCD patients with low soft sign scores and control subjects. Caudate and lenticular nucleus volumes did not differ between groups.

Original language	English (US)
Pages (from-to)	143-150
Number of pages	8
Journal	Psychiatry Research: Neuroimaging
Volume	50
Issue number	3
DOIs	https://doi.org/10.1016/0925-4927(93)90026-E
State	Published - Oct 1993
Externally published	Yes

Keywords

Neuroanatomy
caudate nucleus
cerebral ventricles

ASJC Scopus subject areas

Neuroscience (miscellaneous)
Radiology Nuclear Medicine and imaging
Psychiatry and Mental health

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10.1016/0925-4927(93)90026-E

Cite this

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title = "Computed tomography and neurological soft signs in obsessive-compulsive disorder",

abstract = "Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores and control subjects. Neuroanatomical structures were measured using quantitative volumetric analysis. OCD patients with high soft sign scores had significantly increased ventricular volumes compared with OCD patients with low soft sign scores and control subjects. Caudate and lenticular nucleus volumes did not differ between groups.",

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note = "Funding Information: Acknowledgment. This work was supported by a BRSG grant (Dr. Stem and Dr. Hollander), a NARSAD Young lnvestigator Award (Dr. Stein), and a Research Scientist Development Award {MH-007SO) (Dr. Hniianderi.",

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AU - Stein, Dan J.

AU - Hollander, Eric

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AU - Hilal, Sadek

AU - Liebowitz, Michael R.

AU - Klein, Donald F.

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AB - Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores and control subjects. Neuroanatomical structures were measured using quantitative volumetric analysis. OCD patients with high soft sign scores had significantly increased ventricular volumes compared with OCD patients with low soft sign scores and control subjects. Caudate and lenticular nucleus volumes did not differ between groups.

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KW - cerebral ventricles

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Computed tomography and neurological soft signs in obsessive-compulsive disorder

Abstract

Keywords

ASJC Scopus subject areas

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