Computed tomography and neurological soft signs in obsessive-compulsive disorder

Dan J. Stein, Eric Hollander, Chan Stephen, Concetta M. DeCaria, Sadek Hilal, Michael R. Liebowitz, Donald F. Klein

Research output: Contribution to journalArticle

48 Scopus citations

Abstract

Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores and control subjects. Neuroanatomical structures were measured using quantitative volumetric analysis. OCD patients with high soft sign scores had significantly increased ventricular volumes compared with OCD patients with low soft sign scores and control subjects. Caudate and lenticular nucleus volumes did not differ between groups.

Original languageEnglish (US)
Pages (from-to)143-150
Number of pages8
JournalPsychiatry Research: Neuroimaging
Volume50
Issue number3
DOIs
Publication statusPublished - Oct 1993
Externally publishedYes

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Keywords

  • Neuroanatomy
  • caudate nucleus
  • cerebral ventricles

ASJC Scopus subject areas

  • Neuroscience (miscellaneous)
  • Radiology Nuclear Medicine and imaging
  • Psychiatry and Mental health

Cite this

Stein, D. J., Hollander, E., Stephen, C., DeCaria, C. M., Hilal, S., Liebowitz, M. R., & Klein, D. F. (1993). Computed tomography and neurological soft signs in obsessive-compulsive disorder. Psychiatry Research: Neuroimaging, 50(3), 143-150. https://doi.org/10.1016/0925-4927(93)90026-E