Computed tomography and neurological soft signs in obsessive-compulsive disorder

Dan J. Stein, Eric Hollander, Stephen Chan, Concetta M. DeCaria, Sadek Hilal, Michael R. Liebowitz, Donald F. Klein

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Computed tomography was used to compare the following three groups: obsessive-compulsive disorder (OCD) patients with high scores on a soft neurological sign examination, OCD patients with low soft neurological sign scores, and control subjects. Neuroanatomical structures were measured using quantitative volumetric analysis. OCD patients with high soft sign scores had significantly increased ventricular volumes compared with OCD patients with low soft sign scores and control subjects. Caudate and lenticular nucleus volumes did not differ between groups.

Original languageEnglish (US)
Pages (from-to)143-150
Number of pages8
JournalPsychiatry Research
Volume50
Issue number3
StatePublished - Oct 1993
Externally publishedYes

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Obsessive-Compulsive Disorder
Tomography
Corpus Striatum
Caudate Nucleus
Neurologic Examination

Keywords

  • caudate nucleus
  • cerebral ventricles
  • Neuroanatomy

ASJC Scopus subject areas

  • Psychology(all)
  • Biological Psychiatry
  • Psychiatry and Mental health
  • Radiology Nuclear Medicine and imaging

Cite this

Stein, D. J., Hollander, E., Chan, S., DeCaria, C. M., Hilal, S., Liebowitz, M. R., & Klein, D. F. (1993). Computed tomography and neurological soft signs in obsessive-compulsive disorder. Psychiatry Research, 50(3), 143-150.

Computed tomography and neurological soft signs in obsessive-compulsive disorder. / Stein, Dan J.; Hollander, Eric; Chan, Stephen; DeCaria, Concetta M.; Hilal, Sadek; Liebowitz, Michael R.; Klein, Donald F.

In: Psychiatry Research, Vol. 50, No. 3, 10.1993, p. 143-150.

Research output: Contribution to journalArticle

Stein, DJ, Hollander, E, Chan, S, DeCaria, CM, Hilal, S, Liebowitz, MR & Klein, DF 1993, 'Computed tomography and neurological soft signs in obsessive-compulsive disorder', Psychiatry Research, vol. 50, no. 3, pp. 143-150.
Stein DJ, Hollander E, Chan S, DeCaria CM, Hilal S, Liebowitz MR et al. Computed tomography and neurological soft signs in obsessive-compulsive disorder. Psychiatry Research. 1993 Oct;50(3):143-150.
Stein, Dan J. ; Hollander, Eric ; Chan, Stephen ; DeCaria, Concetta M. ; Hilal, Sadek ; Liebowitz, Michael R. ; Klein, Donald F. / Computed tomography and neurological soft signs in obsessive-compulsive disorder. In: Psychiatry Research. 1993 ; Vol. 50, No. 3. pp. 143-150.
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