Comparison of recovery of propofol and methohexital sedation using an infusion pump.

M. Cohen, S. Eisig, R. A. Kraut

Research output: Contribution to journalArticle

4 Scopus citations

Abstract

Two sedative anesthetic agents administered by an infusion pump were compared during third molar surgery. Forty American Society of Anesthesiologists (ASA) class I or II volunteers were randomly allocated to two groups. All subjects received supplemental oxygen via a nasal hood, fentanyl (0.0007 mg/kg intravenous [i.v.] bolus), and midazolam (1 mg/2 min) titrated to effect. Patients then received either 0.3 mg/kg of methohexital or 0.5 mg/kg of propofol via an infusion pump. Upon completion of the bolus, a continuous infusion of 0.05 mg/kg/min methohexital or 0.066 mg/kg/min propofol was administered throughout the procedure. Hemo-dynamic and respiratory parameters and psychomotor performance were compared for the two groups and no significant differences were found. The continuous infusion method maintained a steady level of sedation. Patients receiving propofol had a smoother sedation as judged by the surgeon and anesthetist.

Original languageEnglish (US)
Pages (from-to)9-13
Number of pages5
JournalAnesthesia progress
Volume43
Issue number1
StatePublished - Dec 1 1996

ASJC Scopus subject areas

  • Anesthesiology and Pain Medicine

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