TRANSPLANTATION HEPATIQUE ET RENALE DANS LE TRAITEMENT DE L'HYPEROXALURIE DE TYPE I

Translated title of the contribution: Combined hepatic and renal transplantation for primary hyperoxaluria type I

P. Jouvet, P. Hubert, D. Jan, P. Niaudet, A. Beringer, C. Narcy, M. Daudon, M. Broyer, Y. Revillon

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

Hyperoxaluria type I (HPI) is a metabolic disorder secondary to liver alanine glyoxylate aminotransferase deficiency. Renal failure occurs due to the excessive production and precipitation of oxalate in the kidney. Combined liver-renal transplantation is the correct treatment for this condition when end-stage renal failure occurs as with renal transplantation alone the risk of recurrence of the same pathology in the transplanted kidney would be high. We report the case of a 4 year-old child with HPI suffering from terminal renal failure in whom a hepato-renal transplantation was performed: six months later, creatinine clearance was 62 ml/min/1.73 m2 and liver function tests were normal.

Original languageFrench
Pages (from-to)637-639
Number of pages3
JournalArchives Francaises de Pediatrie
Volume48
Issue number9
Publication statusPublished - Jan 1 1991
Externally publishedYes

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Keywords

  • child
  • hyperoxaluria
  • kidney failure, chronic
  • liver
  • metabolism, inborn errors
  • transplantation

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health

Cite this

Jouvet, P., Hubert, P., Jan, D., Niaudet, P., Beringer, A., Narcy, C., ... Revillon, Y. (1991). TRANSPLANTATION HEPATIQUE ET RENALE DANS LE TRAITEMENT DE L'HYPEROXALURIE DE TYPE I. Archives Francaises de Pediatrie, 48(9), 637-639.