Cluster attacks responsive to recreational cannabis and dronabinol

Matthew S. Robbins, Sara Tarshish, Seymour Solomon, Brian M. Grosberg

Research output: Contribution to journalArticle

23 Citations (Scopus)

Abstract

Pharmacological preparations of cannabinoid compounds have a variety of therapeutic uses in medicine, including different pain syndromes, but have not been previously reported as beneficial for cluster headache. We present a patient with cluster headache who was refractory to multiple acute and preventive medications but successfully aborted his attacks with recreational marijuana use; subsequent use of dronabinol provided equally effective pain relief. The beneficial effect may be related to the high concentration of cannabinoid receptors in the hypothalamus, which has been implicated as a site of dysfunction in neuroimaging studies of patients with cluster headache.

Original languageEnglish (US)
Pages (from-to)914-916
Number of pages3
JournalHeadache
Volume49
Issue number6
DOIs
StatePublished - Jun 2009

Fingerprint

Cluster Headache
Dronabinol
Cannabis
Pain
Cannabinoid Receptors
Cannabinoids
Therapeutic Uses
Neuroimaging
Hypothalamus
Medicine
Pharmacology

Keywords

  • Cannabis
  • Cluster headache
  • Dronabinol

ASJC Scopus subject areas

  • Clinical Neurology
  • Neurology

Cite this

Cluster attacks responsive to recreational cannabis and dronabinol. / Robbins, Matthew S.; Tarshish, Sara; Solomon, Seymour; Grosberg, Brian M.

In: Headache, Vol. 49, No. 6, 06.2009, p. 914-916.

Research output: Contribution to journalArticle

Robbins, Matthew S. ; Tarshish, Sara ; Solomon, Seymour ; Grosberg, Brian M. / Cluster attacks responsive to recreational cannabis and dronabinol. In: Headache. 2009 ; Vol. 49, No. 6. pp. 914-916.
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