Characteristics of men with untreated LUTS interested in over-the-counter tamsulosin

Claus G. Roehrborn, Franklin C. Lowe, Marc Gittelman, Jan M. Wruck, Anna E. Verbeek

Research output: Contribution to journalArticle

Abstract

INTRODUCTION: Treatment for lower urinary tract symptoms (LUTS) is often delayed, as it is considered a natural progression of aging. We described baseline demographic and clinical characteristics of men currently not using prescription medications for benign prostatic hyperplasia (BPH) but interested in self-directed use of over-the-counter (OTC) tamsulosin and who had participated in OTC tamsulosin-simulated studies. MATERIALS AND METHODS: Pooled baseline data from four OTC tamsulosin-simulated studies were analyzed for men who were currently not using BPH prescription medication and who believed that OTC tamsulosin was appropriate for use or were interested in purchasing it. Data from the OTC-simulated studies for men using BPH prescription medication and from the BPH registry, which included men diagnosed with BPH, were used for comparison. RESULTS: Overall, 3285 non-prescription-using men (mean age +/- standard deviation [SD], 60.6 +/- 11.6 years) were included. Average American Urological Association Symptom Index (AUA-SI) total score was 17.6; 25.5% reported urinary symptoms for > 5 years. Overall, 46.7% of these men had > 1 visit/year with their physicians. Baseline characteristics of prescription users from the OTC-simulated studies (n = 364; mean age ± SD, 68.3 +/- 9.1 years; mean AUA-SI score, 18.5) and of men from the BPH registry (n = 5042; 64.8 +/- 10 years; 11.6) were similar to those of non-prescription users. CONCLUSIONS: Non-prescription users had long term moderate-to-severe male LUTS, yet remained untreated; self-management may be a viable alternative strategy for this population. Disease characteristics of men not using BPH prescription medication and interested in using OTC tamsulosin were similar to those using BPH medication or diagnosed with BPH.

Original languageEnglish (US)
Pages (from-to)9821-9828
Number of pages8
JournalThe Canadian journal of urology
Volume26
Issue number4
StatePublished - Aug 1 2019

Fingerprint

tamsulosin
Lower Urinary Tract Symptoms
Prostatic Hyperplasia
Prescriptions
Registries
Self Care

ASJC Scopus subject areas

  • Urology

Cite this

Roehrborn, C. G., Lowe, F. C., Gittelman, M., Wruck, J. M., & Verbeek, A. E. (2019). Characteristics of men with untreated LUTS interested in over-the-counter tamsulosin. The Canadian journal of urology, 26(4), 9821-9828.

Characteristics of men with untreated LUTS interested in over-the-counter tamsulosin. / Roehrborn, Claus G.; Lowe, Franklin C.; Gittelman, Marc; Wruck, Jan M.; Verbeek, Anna E.

In: The Canadian journal of urology, Vol. 26, No. 4, 01.08.2019, p. 9821-9828.

Research output: Contribution to journalArticle

Roehrborn, CG, Lowe, FC, Gittelman, M, Wruck, JM & Verbeek, AE 2019, 'Characteristics of men with untreated LUTS interested in over-the-counter tamsulosin', The Canadian journal of urology, vol. 26, no. 4, pp. 9821-9828.
Roehrborn, Claus G. ; Lowe, Franklin C. ; Gittelman, Marc ; Wruck, Jan M. ; Verbeek, Anna E. / Characteristics of men with untreated LUTS interested in over-the-counter tamsulosin. In: The Canadian journal of urology. 2019 ; Vol. 26, No. 4. pp. 9821-9828.
@article{8479829cb3f842ae900f840136d254e3,
title = "Characteristics of men with untreated LUTS interested in over-the-counter tamsulosin",
abstract = "INTRODUCTION: Treatment for lower urinary tract symptoms (LUTS) is often delayed, as it is considered a natural progression of aging. We described baseline demographic and clinical characteristics of men currently not using prescription medications for benign prostatic hyperplasia (BPH) but interested in self-directed use of over-the-counter (OTC) tamsulosin and who had participated in OTC tamsulosin-simulated studies. MATERIALS AND METHODS: Pooled baseline data from four OTC tamsulosin-simulated studies were analyzed for men who were currently not using BPH prescription medication and who believed that OTC tamsulosin was appropriate for use or were interested in purchasing it. Data from the OTC-simulated studies for men using BPH prescription medication and from the BPH registry, which included men diagnosed with BPH, were used for comparison. RESULTS: Overall, 3285 non-prescription-using men (mean age +/- standard deviation [SD], 60.6 +/- 11.6 years) were included. Average American Urological Association Symptom Index (AUA-SI) total score was 17.6; 25.5{\%} reported urinary symptoms for > 5 years. Overall, 46.7{\%} of these men had > 1 visit/year with their physicians. Baseline characteristics of prescription users from the OTC-simulated studies (n = 364; mean age ± SD, 68.3 +/- 9.1 years; mean AUA-SI score, 18.5) and of men from the BPH registry (n = 5042; 64.8 +/- 10 years; 11.6) were similar to those of non-prescription users. CONCLUSIONS: Non-prescription users had long term moderate-to-severe male LUTS, yet remained untreated; self-management may be a viable alternative strategy for this population. Disease characteristics of men not using BPH prescription medication and interested in using OTC tamsulosin were similar to those using BPH medication or diagnosed with BPH.",
author = "Roehrborn, {Claus G.} and Lowe, {Franklin C.} and Marc Gittelman and Wruck, {Jan M.} and Verbeek, {Anna E.}",
year = "2019",
month = "8",
day = "1",
language = "English (US)",
volume = "26",
pages = "9821--9828",
journal = "Canadian Journal of Urology",
issn = "1195-9479",
publisher = "Canadian Journal of Urology",
number = "4",

}

TY - JOUR

T1 - Characteristics of men with untreated LUTS interested in over-the-counter tamsulosin

AU - Roehrborn, Claus G.

AU - Lowe, Franklin C.

AU - Gittelman, Marc

AU - Wruck, Jan M.

AU - Verbeek, Anna E.

PY - 2019/8/1

Y1 - 2019/8/1

N2 - INTRODUCTION: Treatment for lower urinary tract symptoms (LUTS) is often delayed, as it is considered a natural progression of aging. We described baseline demographic and clinical characteristics of men currently not using prescription medications for benign prostatic hyperplasia (BPH) but interested in self-directed use of over-the-counter (OTC) tamsulosin and who had participated in OTC tamsulosin-simulated studies. MATERIALS AND METHODS: Pooled baseline data from four OTC tamsulosin-simulated studies were analyzed for men who were currently not using BPH prescription medication and who believed that OTC tamsulosin was appropriate for use or were interested in purchasing it. Data from the OTC-simulated studies for men using BPH prescription medication and from the BPH registry, which included men diagnosed with BPH, were used for comparison. RESULTS: Overall, 3285 non-prescription-using men (mean age +/- standard deviation [SD], 60.6 +/- 11.6 years) were included. Average American Urological Association Symptom Index (AUA-SI) total score was 17.6; 25.5% reported urinary symptoms for > 5 years. Overall, 46.7% of these men had > 1 visit/year with their physicians. Baseline characteristics of prescription users from the OTC-simulated studies (n = 364; mean age ± SD, 68.3 +/- 9.1 years; mean AUA-SI score, 18.5) and of men from the BPH registry (n = 5042; 64.8 +/- 10 years; 11.6) were similar to those of non-prescription users. CONCLUSIONS: Non-prescription users had long term moderate-to-severe male LUTS, yet remained untreated; self-management may be a viable alternative strategy for this population. Disease characteristics of men not using BPH prescription medication and interested in using OTC tamsulosin were similar to those using BPH medication or diagnosed with BPH.

AB - INTRODUCTION: Treatment for lower urinary tract symptoms (LUTS) is often delayed, as it is considered a natural progression of aging. We described baseline demographic and clinical characteristics of men currently not using prescription medications for benign prostatic hyperplasia (BPH) but interested in self-directed use of over-the-counter (OTC) tamsulosin and who had participated in OTC tamsulosin-simulated studies. MATERIALS AND METHODS: Pooled baseline data from four OTC tamsulosin-simulated studies were analyzed for men who were currently not using BPH prescription medication and who believed that OTC tamsulosin was appropriate for use or were interested in purchasing it. Data from the OTC-simulated studies for men using BPH prescription medication and from the BPH registry, which included men diagnosed with BPH, were used for comparison. RESULTS: Overall, 3285 non-prescription-using men (mean age +/- standard deviation [SD], 60.6 +/- 11.6 years) were included. Average American Urological Association Symptom Index (AUA-SI) total score was 17.6; 25.5% reported urinary symptoms for > 5 years. Overall, 46.7% of these men had > 1 visit/year with their physicians. Baseline characteristics of prescription users from the OTC-simulated studies (n = 364; mean age ± SD, 68.3 +/- 9.1 years; mean AUA-SI score, 18.5) and of men from the BPH registry (n = 5042; 64.8 +/- 10 years; 11.6) were similar to those of non-prescription users. CONCLUSIONS: Non-prescription users had long term moderate-to-severe male LUTS, yet remained untreated; self-management may be a viable alternative strategy for this population. Disease characteristics of men not using BPH prescription medication and interested in using OTC tamsulosin were similar to those using BPH medication or diagnosed with BPH.

UR - http://www.scopus.com/inward/record.url?scp=85071771592&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=85071771592&partnerID=8YFLogxK

M3 - Article

C2 - 31469636

AN - SCOPUS:85071771592

VL - 26

SP - 9821

EP - 9828

JO - Canadian Journal of Urology

JF - Canadian Journal of Urology

SN - 1195-9479

IS - 4

ER -