Changes in prescribing of antiviral medications for influenza associated with new treatment guidelines

Adam L. Hersh, Judith H. Maselli, Michael D. Cabana

Research output: Contribution to journalArticle

11 Scopus citations


In 2006, the Centers for Disease Control and Prevention recommended discontinuing the use of adamantanes (amantadine and rimantadine) to treat influenza because of high levels of resistance to this class of antivirals. We examined changes in prescribing practices resulting fromthis recommendation and found that prescribing of adamantanes declined nationwide,with these drugs accounting for approximately 40% of the antivirals prescribed for influenza from 2000 to 2005 and only 2% in 2006. This finding provides evidence of a rapid change in clinical practice associated with the dissemination of treatment guidelines. Evaluating the effectiveness with which public health recommendations are translated into practice is important given the ongoing emergence of resistance to antiviral drugs and a novel H1N1 influenza virus.

Original languageEnglish (US)
Pages (from-to)S362-S364
JournalAmerican journal of public health
Issue numberSUPPL. 2
Publication statusPublished - Oct 22 2009
Externally publishedYes


ASJC Scopus subject areas

  • Public Health, Environmental and Occupational Health

Cite this